Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
P32245 melanocortin 4 receptor G-protein coupled receptor 149 0.535 0.692 9.2E-04 0.400 None 0.977 43 6 1999 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.400 None 0.969 32 0 1997 2020
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.400 None 0.944 18 2 1997 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.330 None 1.000 4 2 2011 2019
Entrez Id: 109
Gene Symbol: ADCY3
ADCY3
O60266 adenylate cyclase 3 47 0.678 0.615 2.0E-11 0.310 None 1.000 1 0 2018 2018
Entrez Id: 3778
Gene Symbol: KCNMA1
KCNMA1
Q12791 potassium calcium-activated channel subfamily M alpha 1 Ion channel 205 0.518 0.846 1.00 0.300 None 1.000 1 0 2011 2011
Entrez Id: 283455
Gene Symbol: KSR2
KSR2
Q6VAB6 kinase suppressor of ras 2 Kinase 27 0.743 0.231 1.00 0.300 None 1.000 1 0 2018 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.150 None 1.000 5 4 2009 2012
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.100 None 1.000 14 0 2003 2019
Entrez Id: 79068
Gene Symbol: FTO
FTO
Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.100 None 1.000 12 3 2007 2018
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.080 None 1.000 8 1 1999 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.080 None 1.000 8 0 2009 2019
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
P81133 SIM bHLH transcription factor 1 Transcription factor 84 0.626 0.654 1.00 0.070 None 1.000 7 1 2000 2017
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 140 0.548 0.615 2.7E-09 0.060 None 1.000 6 1 2002 2018
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
P13945 adrenoceptor beta 3 G-protein coupled receptor 142 0.533 0.731 2.5E-07 0.050 None 0.600 5 1 1995 2018
Entrez Id: 2572
Gene Symbol: GAD2
GAD2
Q05329 glutamate decarboxylase 2 Enzyme 173 0.529 0.731 0.75 0.050 None 1.000 5 0 2003 2006
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 1.000 4 0 1999 2019
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.040 None 0.750 4 1 2008 2015
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.040 None 1.000 4 0 2012 2014
Entrez Id: 364
Gene Symbol: AQP7
AQP7
O14520 aquaporin 7 Ion channel 34 0.670 0.462 4.1E-16 0.040 None 0.750 4 0 2007 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 0 2003 2017
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
Q9NST1 patatin like phospholipase domain containing 3 Enzyme 132 0.556 0.692 5.7E-08 0.030 None 1.000 3 1 2010 2013
Entrez Id: 7350
Gene Symbol: UCP1
UCP1
P25874 uncoupling protein 1 Transporter 124 0.545 0.769 1.7E-11 0.030 None 0.667 3 0 2009 2019
Entrez Id: 181
Gene Symbol: AGRP
AGRP
O00253 agouti related neuropeptide Signaling 233 0.488 0.769 7.0E-04 0.030 None 1.000 3 0 2001 2018
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 408 0.432 0.885 3.0E-02 0.030 None 1.000 3 0 2002 2020