Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
P02458 collagen type II alpha 1 chain 443 0.474 0.724 1.00 0.500 0.895 43 4 1993 2016
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
Q92765 frizzled related protein enzyme modulator; receptor; signaling molecule 57 0.598 0.448 1.3E-03 0.500 0.950 21 2 1998 2016
Entrez Id: 1311
Gene Symbol: COMP
COMP
P49747 cartilage oligomeric matrix protein 142 0.577 0.586 1.2E-09 0.500 0.944 19 0 1995 2017
Entrez Id: 4148
Gene Symbol: MATN3
MATN3
O15232 matrilin 3 receptor 57 0.685 0.172 5.2E-08 0.490 1.000 9 1 2002 2012
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
O94788 aldehyde dehydrogenase 1 family member A2 oxidoreductase 45 0.621 0.552 0.46 0.410 1.000 2 1 2014 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.400 0.974 119 3 1992 2018
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
P43026 growth differentiation factor 5 signaling molecule 217 0.557 0.517 0.68 0.400 0.972 38 2 2007 2017
Entrez Id: 54829
Gene Symbol: ASPN
ASPN
Q9BXN1 asporin 29 0.672 0.345 8.4E-08 0.400 0.960 25 1 2005 2016
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 transcription factor 273 0.462 0.862 0.84 0.400 1.000 22 3 2004 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.390 1.000 10 0 2002 2016
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 runt related transcription factor 2 nucleic acid binding; transcription factor 292 0.490 0.621 0.96 0.370 1.000 8 0 2008 2017
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor cell adhesion molecule; receptor 232 0.472 0.724 3.4E-16 0.360 0.750 7 1 2005 2014
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
P36222 chitinase 3 like 1 167 0.502 0.793 8.5E-06 0.340 1.000 5 0 1993 2016
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 transferase 171 0.499 0.690 7.0E-18 0.340 1.000 5 0 2008 2017
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.330 1.000 5 0 2004 2013
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha signaling molecule 274 0.456 0.828 1.4E-02 0.330 1.000 4 0 2007 2016
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
P19875 C-X-C motif chemokine ligand 2 signaling molecule 101 0.555 0.690 4.2E-07 0.330 1.000 3 0 2004 2016
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
P26447 S100 calcium binding protein A4 calcium-binding protein; signaling molecule 194 0.483 0.621 6.7E-03 0.320 1.000 2 0 2006 2006
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 266 0.456 0.793 5.7E-05 0.310 1.000 3 0 2006 2009
Entrez Id: 2023
Gene Symbol: ENO1
ENO1
P06733 enolase 1 lyase 149 0.516 0.828 1.7E-05 0.310 1.000 2 0 2005 2009
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
P08123 collagen type I alpha 2 chain 216 0.526 0.724 1.00 0.310 1.000 2 0 2007 2009
Entrez Id: 5352
Gene Symbol: PLOD2
PLOD2
O00469 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 oxidoreductase 79 0.621 0.517 5.8E-08 0.310 1.000 2 0 2009 2014
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
Q9HBA0 transient receptor potential cation channel subfamily V member 4 transporter 289 0.519 0.759 2.6E-16 0.310 1.000 2 0 2011 2016
Entrez Id: 1509
Gene Symbol: CTSD
CTSD
P07339 cathepsin D hydrolase; protease 175 0.505 0.759 1.1E-03 0.310 1.000 2 0 1995 2009
Entrez Id: 652
Gene Symbol: BMP4
BMP4
P12644 bone morphogenetic protein 4 signaling molecule 224 0.477 0.724 0.96 0.310 1.000 2 0 2006 2010