Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 1.000 0.910 163 13 1987 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 195 0.494 0.621 1.2E-23 0.730 1.000 5 3 2002 2015
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 nucleic acid binding; transcription factor 264 0.467 0.828 1.00 0.700 1.000 18 0 1987 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.470 1.000 9 1 2005 2017
Entrez Id: 2914
Gene Symbol: GRM4
GRM4
Q14833 glutamate metabotropic receptor 4 receptor 19 0.720 0.172 0.99 0.430 1.000 4 1 2013 2017
Entrez Id: 7486
Gene Symbol: WRN
WRN
Q14191 Werner syndrome RecQ like helicase nucleic acid binding 138 0.545 0.586 3.1E-33 0.420 1.000 2 0 2006 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 1.000 40 0 1997 2018
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 runt related transcription factor 2 nucleic acid binding; transcription factor 292 0.490 0.621 0.96 0.400 0.966 32 0 2000 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 0.952 22 0 1997 2016
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.400 1.000 22 0 1999 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.400 1.000 12 0 1991 2014
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.370 1.000 8 0 1994 2015
Entrez Id: 1719
Gene Symbol: DHFR
DHFR
P00374 dihydrofolate reductase oxidoreductase 129 0.540 0.759 3.7E-02 0.370 1.000 7 0 2003 2016
Entrez Id: 3756
Gene Symbol: KCNH1
KCNH1
O95259 potassium voltage-gated channel subfamily H member 1 117 0.607 0.655 0.62 0.360 1.000 6 0 2012 2016
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 205 0.477 0.690 0.94 0.350 1.000 5 0 2010 2018
Entrez Id: 7262
Gene Symbol: PHLDA2
PHLDA2
Q53GA4 pleckstrin homology like domain family A member 2 16 0.752 0.345 0.16 0.350 1.000 5 0 2012 2016
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit 425 0.421 0.759 1.00 0.340 1.000 5 0 2004 2016
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 398 0.406 0.828 7.1E-02 0.340 0.750 5 1 2007 2016
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit nucleic acid binding; transcription factor 213 0.473 0.828 0.65 0.340 1.000 5 0 1994 2017
Entrez Id: 5981
Gene Symbol: RFC1
RFC1
P35251 replication factor C subunit 1 hydrolase; nucleic acid binding; phosphatase 54 0.614 0.552 0.97 0.340 1.000 5 0 2003 2009
Entrez Id: 4015
Gene Symbol: LOX
LOX
P28300 lysyl oxidase 187 0.488 0.793 0.99 0.330 1.000 4 1 1997 2014
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 Wilms tumor 1 nucleic acid binding; transcription factor 327 0.444 0.690 1.00 0.330 1.000 4 0 1997 2017
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 nucleic acid binding; receptor; transcription factor 263 0.455 0.793 6.2E-09 0.330 1.000 3 0 2007 2013
Entrez Id: 407050
Gene Symbol: MIR93
MIR93
microRNA 93 71 0.586 0.621 0.320 1.000 3 0 2012 2016
Entrez Id: 1965
Gene Symbol: EIF2S1
EIF2S1
P05198 eukaryotic translation initiation factor 2 subunit alpha nucleic acid binding 62 0.598 0.517 0.97 0.310 1.000 2 0 2004 2012