Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.900 1.000 26 1 1993 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.700 1.000 27 1 1993 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.700 1.000 19 1 1996 2015
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.700 0.923 17 0 1998 2015
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.610 1.000 3 1 2004 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.540 1.000 6 0 2003 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.520 3 0 2005 2015
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1
P00995 serine peptidase inhibitor, Kazal type 1 125 0.536 0.621 0.33 0.410 2 0 2003 2010
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.400 1.000 14 0 2003 2016
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
O00255 menin 1 273 0.463 0.724 1.00 0.390 0.889 11 0 1991 2011
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.380 1.000 10 0 2003 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.370 1.000 8 0 2003 2016
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 135 0.557 0.483 2.0E-02 0.360 1.000 9 0 1999 2016
Entrez Id: 6752
Gene Symbol: SSTR2
SSTR2
P30874 somatostatin receptor 2 receptor 105 0.551 0.517 0.43 0.360 1.000 9 0 2003 2010
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.360 1.000 8 0 2004 2015
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.360 1.000 7 0 2001 2013
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.350 0.667 8 0 1999 2013
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 467 0.389 0.862 2.1E-07 0.350 1.000 6 0 1999 2017
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase hydrolase; protease 325 0.434 0.690 2.1E-06 0.350 1.000 5 0 1999 2009
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.350 1.000 5 0 2003 2008
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.350 0.800 5 0 2002 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.340 1.000 6 0 2000 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.340 1.000 5 0 1991 2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 signaling molecule 847 0.336 0.931 0.17 0.340 1.000 5 0 2002 2014
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Q13421 mesothelin extracellular matrix protein 86 0.565 0.483 8.2E-23 0.340 1.000 5 0 2002 2009