Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.700 None 0.983 2577 53 1997 2020
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced kinase 1 Kinase 209 0.516 0.769 1.9E-10 0.600 None 0.987 376 12 2002 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.600 None 0.974 304 20 1998 2020
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.600 None 0.979 141 3 1989 2020
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Q99497 Parkinsonism associated deglycase Enzyme 161 0.535 0.808 0.75 0.600 None 0.973 110 8 2003 2020
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
P27338 monoamine oxidase B 152 0.533 0.808 1.00 0.600 None 0.991 110 1 1993 2020
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.600 None 0.931 58 3 1995 2020
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
Q9NQ11 ATPase cation transporting 13A2 160 0.566 0.577 9.0E-09 0.600 strong 0.946 56 4 2007 2019
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2
Q05940 solute carrier family 18 member A2 Transporter 150 0.554 0.769 7.6E-02 0.600 None 0.966 29 1 1996 2020
Entrez Id: 1644
Gene Symbol: DDC
DDC
P20711 dopa decarboxylase 164 0.535 0.769 3.8E-08 0.600 None 1.000 28 0 1988 2019
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
P21728 dopamine receptor D1 G-protein coupled receptor 181 0.529 0.808 0.96 0.570 None 1.000 10 0 1996 2020
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.510 None 1.000 3 0 2009 2019
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.500 None 0.983 987 35 2002 2020
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.500 None 0.989 264 15 2004 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.500 None 0.972 142 40 1999 2019
Entrez Id: 683
Gene Symbol: BST1
BST1
Q10588 bone marrow stromal cell antigen 1 Enzyme 41 0.670 0.423 4.2E-11 0.500 None 0.920 25 8 2009 2019
Entrez Id: 2580
Gene Symbol: GAK
GAK
O14976 cyclin G associated kinase Kinase 13 0.805 0.231 5.2E-03 0.500 None 1.000 18 4 2009 2020
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA
P01903 major histocompatibility complex, class II, DR alpha Immune response 92 0.581 0.769 0.52 0.480 None 1.000 10 1 2010 2015
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.400 None 0.935 185 7 1994 2020
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.400 None 0.983 117 0 1993 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.400 None 0.906 96 6 1995 2020
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.400 None 0.879 58 0 1992 2019
Entrez Id: 55737
Gene Symbol: VPS35
VPS35
Q96QK1 VPS35 retromer complex component Transporter 66 0.656 0.500 0.97 0.400 None 0.931 58 2 2011 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.980 50 0 1999 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.400 None 0.971 35 3 1993 2020