Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha chaperone; membrane traffic protein 176 0.513 0.793 0.90 0.900 strong 0.973 595 34 1997 2018
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced putative kinase 1 kinase; receptor; transferase 96 0.577 0.586 1.0E-10 0.800 strong 0.965 242 7 2002 2018
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase ligase 245 0.464 0.793 0.800 strong 0.964 234 14 1998 2018
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Q99497 Parkinsonism associated deglycase hydrolase; nucleic acid binding; protease; transcription factor 75 0.586 0.552 0.78 0.800 strong 0.963 77 6 2003 2017
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 129 0.545 0.690 3.1E-30 0.700 strong 0.966 692 26 2002 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 transporter 237 0.484 0.690 1.00 0.600 strong 0.850 63 1 1994 2017
Entrez Id: 55737
Gene Symbol: VPS35
VPS35
Q96QK1 VPS35, retromer complex component membrane traffic protein 21 0.713 0.379 0.97 0.600 strong 0.923 43 1 2011 2018
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
P27338 monoamine oxidase B nucleic acid binding; oxidoreductase; transferase 82 0.575 0.724 1.00 0.600 0.974 41 0 1993 2016
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
Q9NQ11 ATPase cation transporting 13A2 83 0.611 0.276 6.7E-09 0.600 strong 0.947 40 4 2007 2018
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 receptor 325 0.454 0.724 0.79 0.600 0.935 39 0 1995 2016
Entrez Id: 4929
Gene Symbol: NR4A2
NR4A2
P43354 nuclear receptor subfamily 4 group A member 2 receptor; transcription factor 111 0.559 0.586 1.00 0.600 limited 0.964 36 1 1999 2018
Entrez Id: 1644
Gene Symbol: DDC
DDC
P20711 dopa decarboxylase 131 0.554 0.621 5.9E-08 0.600 1.000 16 0 1988 2014
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2
Q05940 solute carrier family 18 member A2 105 0.575 0.621 7.3E-02 0.600 1.000 16 1 1997 2016
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
P21728 dopamine receptor D1 114 0.555 0.517 0.94 0.520 1.000 5 0 1996 2013
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 265 0.521 0.724 5.6E-06 0.500 1.000 129 4 2004 2018
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 265 0.492 0.724 7.3E-03 0.500 0.980 107 32 1999 2018
Entrez Id: 683
Gene Symbol: BST1
BST1
Q10588 bone marrow stromal cell antigen 1 hydrolase; lyase 13 0.785 0.345 3.7E-10 0.500 0.813 22 8 2010 2017
Entrez Id: 2643
Gene Symbol: GCH1
GCH1
P30793 GTP cyclohydrolase 1 hydrolase 193 0.534 0.724 0.91 0.500 strong 1.000 17 1 1998 2018
Entrez Id: 2580
Gene Symbol: GAK
GAK
O14976 cyclin G associated kinase chaperone; kinase; transferase 4 0.886 0.103 4.3E-03 0.500 1.000 15 3 2009 2017
Entrez Id: 55532
Gene Symbol: SLC30A10
SLC30A10
Q6XR72 solute carrier family 30 member 10 77 0.602 0.552 0.98 0.500 strong 5 0 1993 2015
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor 373 0.433 0.828 0.99 0.500 2 0 2009 2010
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA
P01903 major histocompatibility complex, class II, DR alpha defense/immunity protein 56 0.616 0.690 0.56 0.490 0.778 11 1 2010 2016
Entrez Id: 254428
Gene Symbol: SLC41A1
SLC41A1
Q8IVJ1 solute carrier family 41 member 1 transporter 8 0.834 0.172 0.68 0.450 limited 1.000 9 4 2011 2017
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor signaling molecule 264 0.463 0.759 0.20 0.400 0.986 73 0 1993 2017
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 312 0.461 0.724 2.2E-23 0.400 0.893 57 0 1992 2014