Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.600 0.960 57 1 1997 2018
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
Q99801 NK3 homeobox 1 nucleic acid binding; transcription factor 19 0.727 0.241 1.9E-03 0.600 1.000 16 0 1999 2013
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.580 1.000 10 0 2002 2018
Entrez Id: 4477
Gene Symbol: MSMB
MSMB
P08118 microseminoprotein beta signaling molecule 101 0.548 0.724 1.6E-02 0.560 1.000 10 0 1998 2011
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 kinase; receptor; transferase 361 0.437 0.793 0.15 0.530 1.000 4 0 2004 2008
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.520 4 0 2007 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.500 0.920 42 1 1994 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.500 0.875 33 1 2000 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.500 1.000 23 1 1994 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.500 1 0 2018 2018
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor nucleic acid binding; receptor; transcription factor 564 0.380 0.793 0.98 0.400 0.970 234 2 1990 2018
Entrez Id: 354
Gene Symbol: KLK3
KLK3
P07288 kallikrein related peptidase 3 hydrolase; protease 153 0.519 0.793 4.8E-06 0.400 0.964 74 0 1992 2016
Entrez Id: 2078
Gene Symbol: ERG
ERG
P11308 ERG, ETS transcription factor nucleic acid binding; signaling molecule; transcription factor 147 0.511 0.690 0.97 0.400 0.969 48 0 2006 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 1.000 30 0 2000 2013
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
O15393 transmembrane serine protease 2 hydrolase; protease 48 0.639 0.414 5.9E-09 0.400 0.923 28 0 2001 2018
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
P31213 steroid 5 alpha-reductase 2 oxidoreductase 82 0.580 0.483 0.400 1.000 26 0 2000 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 0.923 25 0 1997 2013
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 398 0.406 0.828 7.1E-02 0.400 1.000 24 0 2001 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.400 < 0.001 23 0 1997 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 1.000 23 0 1994 2015
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.400 1.000 22 0 1999 2011
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.400 1.000 21 0 2002 2016
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL
Q05823 ribonuclease L 55 0.607 0.552 2.1E-10 0.400 1.000 20 1 2002 2016
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 nucleic acid binding; receptor; transcription factor 297 0.445 0.828 5.4E-08 0.400 1.000 19 0 2004 2016
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 334 0.424 0.724 0.66 0.400 1.000 18 0 1999 2018