Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.500 None 0.978 137 24 1973 2020
Entrez Id: 2006
Gene Symbol: ELN
ELN 		P15502 elastin 545 0.415 0.885 2.1E-14 0.400 None 1.000 21 0 1992 2019
Entrez Id: 4321
Gene Symbol: MMP12
MMP12 		P39900 matrix metallopeptidase 12 Enzyme 216 0.484 0.885 0.400 None 1.000 20 1 1997 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.400 None 1.000 18 0 2001 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.390 None 1.000 10 0 2002 2019
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.370 None 0.857 7 0 1997 2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.360 None 1.000 7 1 2003 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.340 None 1.000 5 0 1998 2019
Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6 		P18564 integrin subunit beta 6 Receptor 92 0.597 0.692 1.6E-22 0.330 None 1.000 3 0 2003 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.330 None 1.000 3 0 2000 2009
Entrez Id: 177
Gene Symbol: AGER
AGER 		Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.320 None 1.000 2 0 2013 2019
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6 		P11509 cytochrome P450 family 2 subfamily A member 6 133 0.556 0.731 5.4E-09 0.310 None 1.000 1 0 2003 2003
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1 		P36897 transforming growth factor beta receptor 1 Kinase 347 0.451 0.885 0.85 0.300 strong 1.000 1 0 2006 2006
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2 		P61812 transforming growth factor beta 2 Signaling 389 0.433 0.885 1.00 0.300 strong 1.000 1 0 2013 2013
Entrez Id: 7043
Gene Symbol: TGFB3
TGFB3 		P10600 transforming growth factor beta 3 Signaling 230 0.498 0.808 0.99 0.300 strong 1.000 1 0 2015 2015
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.300 strong 1.000 1 0 2013 2013
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.300 moderate 1.000 1 0 2013 2013
Entrez Id: 636
Gene Symbol: BICD1
BICD1 		Q96G01 BICD cargo adaptor 1 8 0.821 0.231 1.6E-05 0.130 None 1.000 3 2 2011 2014
Entrez Id: 9374
Gene Symbol: PPT2
PPT2 		Q9UMR5 palmitoyl-protein thioesterase 2 Enzyme 27 0.751 0.500 4.5E-03 0.110 None 1.000 1 1 2014 2014
Entrez Id: 6636
Gene Symbol: SNRPF
SNRPF 		P62306 small nuclear ribonucleoprotein polypeptide F Nucleic acid binding 14 0.805 0.154 0.79 0.110 None 1.000 1 1 2014 2014
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 0.972 71 0 1999 2020
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		P08246 elastase, neutrophil expressed Enzyme 346 0.447 0.846 1.2E-03 0.100 None 1.000 25 0 1981 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.947 19 0 2001 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.100 None 1.000 13 1 2004 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 0 2009 2019