Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.912 57 0 1976 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.700 None 0.938 48 131 1994 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.974 39 2 1994 2019
Entrez Id: 56244
Gene Symbol: BTNL2
BTNL2
Q9UIR0 butyrophilin like 2 Enzyme modulator 145 0.546 0.808 8.6E-11 0.700 None 1.000 28 25 2005 2019
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
Q8IUH3 RNA binding motif protein 45 557 0.383 0.846 2.1E-10 0.100 None 0.920 25 0 1995 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.100 None 1.000 20 0 1995 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 19 0 2017 2020
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.100 None 0.733 15 1 2003 2018
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.400 None 1.000 12 0 1999 2016
Entrez Id: 311
Gene Symbol: ANXA11
ANXA11
P50995 annexin A11 57 0.650 0.692 4.7E-10 0.500 None 0.909 11 9 2008 2018
Entrez Id: 1056
Gene Symbol: CEL
CEL
P19835 carboxyl ester lipase 172 0.514 0.808 1.5E-06 0.100 None 1.000 11 0 1994 2020
Entrez Id: 10998
Gene Symbol: SLC27A5
SLC27A5
Q9Y2P5 solute carrier family 27 member 5 Transporter 111 0.563 0.769 8.4E-15 0.100 None 1.000 11 0 1994 2020
Entrez Id: 83666
Gene Symbol: PARP9
PARP9
Q8IXQ6 poly(ADP-ribose) polymerase family member 9 116 0.554 0.808 5.0E-09 0.100 None 1.000 11 0 1994 2020
Entrez Id: 3125
Gene Symbol: HLA-DRB3
HLA-DRB3
P79483 major histocompatibility complex, class II, DR beta 3 Immune response 85 0.570 0.885 0.100 None 0.800 10 0 1994 2015
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 Immune response 324 0.453 0.923 5.3E-10 0.390 None 0.900 10 0 1996 2017
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.090 None 1.000 9 0 1986 2019
Entrez Id: 4049
Gene Symbol: LTA
LTA
P01374 lymphotoxin alpha Signaling 353 0.434 0.885 0.20 0.090 None 1.000 9 1 1997 2014
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 504 0.407 0.885 8.9E-03 0.170 None 1.000 8 4 1998 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.080 None 0.875 8 0 1987 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.070 None 1.000 7 0 1998 2019
Entrez Id: 1118
Gene Symbol: CHIT1
CHIT1
Q13231 chitinase 1 142 0.525 0.692 7.2E-16 0.070 None 1.000 7 0 2007 2020
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
P13501 C-C motif chemokine ligand 5 Signaling 514 0.403 0.885 1.8E-03 0.060 None 1.000 6 0 1998 2006
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 427 0.416 0.846 2.4E-02 0.140 None 0.833 6 53 1994 2016
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
P49279 solute carrier family 11 member 1 Transporter 141 0.525 0.846 1.5E-19 0.350 None 1.000 6 1 2000 2012
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.060 None 0.833 6 2 2006 2009