Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 1.000 48 1 1995 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.400 1.000 32 3 2002 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 961 0.320 0.931 6.5E-03 0.400 0.885 26 1 2000 2016
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 nucleic acid binding; signaling molecule; transcription factor 322 0.433 0.828 0.83 0.400 1.000 21 1 2004 2018
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 393 0.421 0.828 0.33 0.370 0.857 8 0 2000 2016
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 531 0.385 0.931 1.5E-14 0.360 1.000 8 1 2002 2015
Entrez Id: 3929
Gene Symbol: LBP
LBP
P18428 lipopolysaccharide binding protein 50 0.627 0.517 6.4E-15 0.360 0.833 6 1 1993 2012
Entrez Id: 4049
Gene Symbol: LTA
LTA
P01374 lymphotoxin alpha signaling molecule 228 0.463 0.862 0.56 0.340 1.000 5 0 1999 2012
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 901 0.323 0.897 0.47 0.340 1.000 5 0 1998 2015
Entrez Id: 133
Gene Symbol: ADM
ADM
P35318 adrenomedullin signaling molecule 246 0.471 0.724 3.5E-02 0.340 1.000 5 0 2004 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.330 0.333 4 1 2009 2015
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
Q15389 angiopoietin 1 signaling molecule 184 0.495 0.690 0.99 0.330 1.000 4 0 2005 2015
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.320 1.000 3 0 2001 2014
Entrez Id: 4282
Gene Symbol: MIF
MIF
P14174 macrophage migration inhibitory factor 256 0.457 0.862 1.2E-02 0.310 1.000 2 0 1999 2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 signaling molecule 847 0.336 0.931 0.17 0.310 < 0.001 2 0 2005 2010
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 kinase; transferase 525 0.387 0.862 1.00 0.310 1.000 2 0 2005 2017
Entrez Id: 5624
Gene Symbol: PROC
PROC
P04070 protein C, inactivator of coagulation factors Va and VIIIa hydrolase; protease 57 0.645 0.586 9.9E-05 0.300 2 0 2002 2007
Entrez Id: 3579
Gene Symbol: CXCR2
CXCR2
P25025 C-X-C motif chemokine receptor 2 192 0.482 0.828 7.4E-03 0.300 1 0 2007 2007
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 enzyme modulator; hydrolase; protease 462 0.391 0.862 0.28 0.300 1 0 2005 2005
Entrez Id: 7045
Gene Symbol: TGFBI
TGFBI
Q15582 transforming growth factor beta induced cell adhesion molecule; signaling molecule 160 0.510 0.724 8.4E-07 0.300 1 0 2017 2017
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
P29274 adenosine A2a receptor receptor 163 0.537 0.690 0.60 0.300 1 0 2017 2017
Entrez Id: 136
Gene Symbol: ADORA2B
ADORA2B
P29275 adenosine A2b receptor receptor 40 0.656 0.483 1.8E-05 0.300 1 0 2017 2017
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
P01563 interferon alpha 2 267 0.459 0.793 0.300 1 0 1987 1987
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 kinase; transferase 345 0.429 0.828 1.0E-01 0.300 1 0 2005 2005
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
P08246 elastase, neutrophil expressed hydrolase; protease 172 0.506 0.759 1.4E-03 0.120 0.500 2 0 2000 2013