Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.981 162 2 1995 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.400 None 0.967 91 3 2001 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.400 None 0.956 90 3 2004 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.400 None 0.974 76 3 2000 2019
Entrez Id: 133
Gene Symbol: ADM
ADM
P35318 adrenomedullin Signaling 405 0.436 0.808 4.1E-02 0.400 None 1.000 23 0 2000 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.400 None 1.000 21 0 1998 2019
Entrez Id: 5624
Gene Symbol: PROC
PROC
P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 200 0.504 0.808 1.9E-05 0.400 None 1.000 21 0 2000 2019
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.400 None 1.000 15 0 2000 2020
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.400 None 1.000 12 1 2003 2019
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
Q15389 angiopoietin 1 Signaling 340 0.446 0.808 0.95 0.400 None 1.000 11 0 2005 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.400 None 1.000 11 0 2005 2020
Entrez Id: 4049
Gene Symbol: LTA
LTA
P01374 lymphotoxin alpha Signaling 353 0.434 0.885 0.20 0.390 None 1.000 10 1 1999 2016
Entrez Id: 3929
Gene Symbol: LBP
LBP
P18428 lipopolysaccharide binding protein 156 0.525 0.808 4.2E-15 0.380 None 0.875 8 2 1993 2018
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.350 None 1.000 6 0 2004 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.330 None 1.000 4 0 2001 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.330 None 0.500 4 1 2009 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.330 None 1.000 4 0 2005 2018
Entrez Id: 7045
Gene Symbol: TGFBI
TGFBI
Q15582 transforming growth factor beta induced Signaling 225 0.484 0.769 6.0E-08 0.330 None 1.000 3 0 2017 2020
Entrez Id: 3579
Gene Symbol: CXCR2
CXCR2
P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 335 0.445 0.923 1.4E-02 0.320 None 0.667 3 0 2007 2020
Entrez Id: 4282
Gene Symbol: MIF
MIF
P14174 macrophage migration inhibitory factor 455 0.412 0.885 1.2E-02 0.320 None 1.000 3 0 1999 2018
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
P29274 adenosine A2a receptor G-protein coupled receptor 213 0.526 0.769 0.60 0.300 None 1.000 1 0 2016 2016
Entrez Id: 136
Gene Symbol: ADORA2B
ADORA2B
P29275 adenosine A2b receptor G-protein coupled receptor 66 0.617 0.692 1.8E-05 0.300 None 1.000 1 0 2016 2016
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
P01563 interferon alpha 2 355 0.442 0.885 0.300 None 1.000 1 0 1987 1987
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.934 151 3 1991 2020