Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 140907
Gene Symbol: SPG19
SPG19 		spastic paraplegia 19 (autosomal dominant) 2 0.931 0.077 0.010 None 1.000 1 0 2002 2002
Entrez Id: 619379
Gene Symbol: SPG29
SPG29 		spastic paraplegia 29 (autosomal dominant) 2 0.931 0.077 0.010 None 1.000 1 0 2005 2005
Entrez Id: 119032
Gene Symbol: BORCS7
BORCS7 		Q96B45 BLOC-1 related complex subunit 7 10 0.890 0.115 2.3E-07 0.200 None 0 0
Entrez Id: 5833
Gene Symbol: PCYT2
PCYT2 		Q99447 phosphate cytidylyltransferase 2, ethanolamine Enzyme 13 0.821 0.192 8.6E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 339855
Gene Symbol: KY
KY 		Q8NBH2 kyphoscoliosis peptidase 39 0.736 0.231 1.5E-10 0.100 None 1.000 1 1 2017 2017
Entrez Id: 51302
Gene Symbol: CYP39A1
CYP39A1 		Q9NYL5 cytochrome P450 family 39 subfamily A member 1 15 0.736 0.231 3.9E-16 0.010 None 1.000 1 0 2014 2014
Entrez Id: 81790
Gene Symbol: RNF170
RNF170 		Q96K19 ring finger protein 170 11 0.861 0.231 0.51 0.010 None 1.000 1 0 2019 2019
Entrez Id: 51308
Gene Symbol: REEP2
REEP2 		Q9BRK0 receptor accessory protein 2 Transporter 26 0.792 0.269 0.44 0.020 None 1.000 2 0 2014 2016
Entrez Id: 10613
Gene Symbol: ERLIN1
ERLIN1 		O75477 ER lipid raft associated 1 33 0.736 0.308 0.18 0.320 None 1.000 3 0 2014 2019
Entrez Id: 118813
Gene Symbol: ZFYVE27
ZFYVE27 		Q5T4F4 zinc finger FYVE-type containing 27 12 0.805 0.308 1.1E-09 0.020 None 1.000 2 0 2006 2019
Entrez Id: 9907
Gene Symbol: AP5Z1
AP5Z1 		O43299 adaptor related protein complex 5 subunit zeta 1 47 0.700 0.346 7.3E-31 0.030 None 0.667 3 0 2010 2015
Entrez Id: 3800
Gene Symbol: KIF5C
KIF5C 		O60282 kinesin family member 5C Cellular structure 33 0.686 0.346 1.00 0.020 None 1.000 2 0 2002 2008
Entrez Id: 23431
Gene Symbol: AP4E1
AP4E1 		Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 72 0.656 0.385 2.8E-03 0.020 None 1.000 2 1 2013 2019
Entrez Id: 11154
Gene Symbol: AP4S1
AP4S1 		Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 64 0.674 0.385 1.7E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6253
Gene Symbol: RTN2
RTN2 		O75298 reticulon 2 43 0.711 0.385 0.42 0.010 None 1.000 1 0 2012 2012
Entrez Id: 85465
Gene Symbol: SELENOI
SELENOI 		Q9C0D9 selenoprotein I Enzyme 29 0.769 0.385 0.64 0.010 None 1.000 1 0 2017 2017
Entrez Id: 65055
Gene Symbol: REEP1
REEP1 		Q9H902 receptor accessory protein 1 Transporter 79 0.653 0.423 0.99 0.400 None 1.000 13 1 2006 2019
Entrez Id: 80821
Gene Symbol: DDHD1
DDHD1 		Q8NEL9 DDHD domain containing 1 Enzyme 38 0.716 0.423 0.90 0.330 limited 1.000 4 0 2005 2018
Entrez Id: 57679
Gene Symbol: ALS2
ALS2 		Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 84 0.647 0.423 8.7E-12 0.030 None 1.000 3 1 2007 2015
Entrez Id: 57760
Gene Symbol: SPG16
SPG16 		spastic paraplegia 16 (complicated, X-linked recessive) 18 0.722 0.423 0.030 None 1.000 3 0 2011 2014
Entrez Id: 9895
Gene Symbol: TECPR2
TECPR2 		O15040 tectonin beta-propeller repeat containing 2 51 0.663 0.423 0.58 0.310 None 1.000 2 0 2012 2016
Entrez Id: 200205
Gene Symbol: IBA57
IBA57 		Q5T440 iron-sulfur cluster assembly factor IBA57 63 0.666 0.423 8.4E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 84188
Gene Symbol: FAR1
FAR1 		Q8WVX9 fatty acyl-CoA reductase 1 22 0.751 0.423 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 123606
Gene Symbol: NIPA1
NIPA1 		Q7RTP0 NIPA magnesium transporter 1 Transporter 50 0.682 0.462 5.9E-03 0.200 None 1.000 11 2 2006 2019
Entrez Id: 113612
Gene Symbol: CYP2U1
CYP2U1 		Q7Z449 cytochrome P450 family 2 subfamily U member 1 34 0.722 0.462 1.4E-03 0.350 strong 1.000 6 0 2012 2018