Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6687
Gene Symbol: SPG7
SPG7
Q9UQ90 SPG7, paraplegin matrix AAA peptidase subunit hydrolase; protease 142 0.542 0.655 3.3E-35 0.700 strong 1.000 16 5 1999 2018
Entrez Id: 80208
Gene Symbol: SPG11
SPG11
Q96JI7 SPG11, spatacsin vesicle trafficking associated 107 0.586 0.483 6.3E-39 0.700 strong 1.000 16 1 2004 2018
Entrez Id: 9420
Gene Symbol: CYP7B1
CYP7B1
O75881 cytochrome P450 family 7 subfamily B member 1 oxidoreductase 102 0.604 0.517 3.2E-06 0.670 strong 1.000 9 2 2008 2018
Entrez Id: 6683
Gene Symbol: SPAST
SPAST
Q9UBP0 spastin cytoskeletal protein 93 0.604 0.517 1.00 0.600 strong 0.981 69 2 2000 2018
Entrez Id: 547
Gene Symbol: KIF1A
KIF1A
Q12756 kinesin family member 1A cytoskeletal protein 154 0.607 0.552 1.00 0.600 strong 1 1 2016 2016
Entrez Id: 10908
Gene Symbol: PNPLA6
PNPLA6
Q8IY17 patatin like phospholipase domain containing 6 hydrolase 137 0.550 0.655 5.9E-13 0.560 strong 1.000 7 0 2008 2016
Entrez Id: 23503
Gene Symbol: ZFYVE26
ZFYVE26
Q68DK2 zinc finger FYVE-type containing 26 56 0.636 0.552 5.8E-23 0.540 strong 1.000 5 0 2008 2014
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
P10809 heat shock protein family D (Hsp60) member 1 226 0.481 0.793 0.99 0.540 strong 1.000 5 1 2002 2013
Entrez Id: 23259
Gene Symbol: DDHD2
DDHD2
O94830 DDHD domain containing 2 hydrolase; membrane traffic protein 33 0.713 0.448 1.1E-10 0.530 strong 1.000 3 0 2013 2018
Entrez Id: 5354
Gene Symbol: PLP1
PLP1
P60201 proteolipid protein 1 structural protein 128 0.577 0.517 0.93 0.520 strong 1.000 6 0 1995 2017
Entrez Id: 79152
Gene Symbol: FA2H
FA2H
Q7L5A8 fatty acid 2-hydroxylase oxidoreductase 60 0.633 0.517 0.13 0.520 strong 1.000 3 0 2010 2011
Entrez Id: 9895
Gene Symbol: TECPR2
TECPR2
O15040 tectonin beta-propeller repeat containing 2 57 0.676 0.345 0.83 0.500 limited 2 0 2013 2016
Entrez Id: 123606
Gene Symbol: NIPA1
NIPA1
Q7RTP0 NIPA magnesium transporter 1 45 0.681 0.379 3.2E-02 0.460 strong 1.000 7 1 2007 2018
Entrez Id: 57704
Gene Symbol: GBA2
GBA2
Q9HCG7 glucosylceramidase beta 2 hydrolase 41 0.690 0.448 3.0E-21 0.410 strong 1.000 2 2 2013 2018
Entrez Id: 51062
Gene Symbol: ATL1
ATL1
Q8WXF7 atlastin GTPase 1 enzyme modulator 71 0.614 0.655 0.99 0.400 strong 0.909 17 1 2001 2018
Entrez Id: 3798
Gene Symbol: KIF5A
KIF5A
Q12840 kinesin family member 5A cytoskeletal protein 63 0.642 0.483 1.00 0.400 strong 1.000 10 0 2003 2014
Entrez Id: 83636
Gene Symbol: C19orf12
C19orf12
Q9NSK7 chromosome 19 open reading frame 12 60 0.667 0.379 0.35 0.400 strong 1 1 2018 2018
Entrez Id: 11160
Gene Symbol: ERLIN2
ERLIN2
O94905 ER lipid raft associated 2 46 0.696 0.448 8.6E-04 0.400 limited 1 1 2018 2018
Entrez Id: 65055
Gene Symbol: REEP1
REEP1
Q9H902 receptor accessory protein 1 receptor; transporter 46 0.707 0.310 0.99 0.380 strong 1.000 8 0 2006 2016
Entrez Id: 23111
Gene Symbol: SPART
SPART
Q8N0X7 spartin 65 0.645 0.586 0.340 strong 1.000 4 0 2002 2013
Entrez Id: 9897
Gene Symbol: WASHC5
WASHC5
Q12768 WASH complex subunit 5 transfer/carrier protein 118 0.602 0.621 0.340 strong 1.000 4 0 2007 2016
Entrez Id: 57679
Gene Symbol: ALS2
ALS2
Q96Q42 ALS2, alsin Rho guanine nucleotide exchange factor 79 0.663 0.310 3.1E-10 0.320 strong 1.000 3 0 2002 2008
Entrez Id: 113612
Gene Symbol: CYP2U1
CYP2U1
Q7Z449 cytochrome P450 family 2 subfamily U member 1 21 0.799 0.241 5.1E-03 0.320 strong 1.000 2 0 2017 2017
Entrez Id: 9907
Gene Symbol: AP5Z1
AP5Z1
O43299 adaptor related protein complex 5 subunit zeta 1 55 0.672 0.345 2.3E-30 0.320 limited 0.500 2 0 2010 2016
Entrez Id: 3897
Gene Symbol: L1CAM
L1CAM
P32004 L1 cell adhesion molecule 206 0.500 0.655 1.00 0.310 strong 1.000 2 0 1994 2013