Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.390 None 1.000 12 0 1995 2017
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.370 None 1.000 11 0 1995 2009
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.370 None 1.000 8 0 2002 2008
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.370 None 1.000 7 0 2002 2008
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.360 None 1.000 8 0 1992 2013
Entrez Id: 30834
Gene Symbol: ZNRD1
ZNRD1
Q9P1U0 zinc ribbon domain containing 1 50 0.653 0.654 0.21 0.360 None 1.000 7 0 2004 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.350 None 1.000 6 0 2006 2011
Entrez Id: 56287
Gene Symbol: GKN1
GKN1
Q9NS71 gastrokine 1 55 0.628 0.615 1.1E-06 0.350 None 1.000 6 0 2004 2019
Entrez Id: 2520
Gene Symbol: GAST
GAST
P01350 gastrin 236 0.485 0.808 2.7E-03 0.340 None 1.000 5 0 2004 2016
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad diadenosine triphosphatase 337 0.444 0.846 5.7E-03 0.340 None 1.000 5 0 2002 2009
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.340 None 1.000 5 0 2005 2018
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.340 None 1.000 5 0 1998 2008
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.330 None 1.000 4 0 2005 2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.330 None 1.000 4 0 2002 2013
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.330 None 1.000 4 0 2006 2007
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
P09237 matrix metallopeptidase 7 Enzyme 320 0.446 0.885 1.0E-09 0.330 None 1.000 4 0 2007 2015
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.320 None 1.000 5 0 2004 2015
Entrez Id: 7372
Gene Symbol: UMPS
UMPS
P11172 uridine monophosphate synthetase 102 0.584 0.615 1.1E-04 0.320 None 1.000 5 0 2005 2008
Entrez Id: 387
Gene Symbol: RHOA
RHOA
P61586 ras homolog family member A Enzyme modulator 193 0.502 0.808 0.60 0.320 None 1.000 4 0 2004 2014
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.320 None 1.000 4 0 2006 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.320 None 1.000 4 0 2003 2009
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.320 None 1.000 3 0 2005 2007
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.320 None 1.000 3 0 2007 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.320 None 1.000 3 0 2006 2009
Entrez Id: 8000
Gene Symbol: PSCA
PSCA
O43653 prostate stem cell antigen 111 0.555 0.615 0.17 0.320 None 1.000 3 0 2000 2015