Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.700 None 0.990 208 5 2003 2020
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.700 None 0.994 178 9 1992 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.680 None 1.000 14 8 1988 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.480 None 1.000 9 4 2003 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.460 None 1.000 13 7 1988 2016
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Q92911 solute carrier family 5 member 5 Transporter 195 0.499 0.769 2.9E-03 0.400 None 1.000 80 0 1997 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.953 64 3 1991 2019
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
P16473 thyroid stimulating hormone receptor G-protein coupled receptor 250 0.486 0.808 3.0E-15 0.400 None 0.906 53 0 1991 2018
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.400 None 0.939 33 2 1999 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.400 None 1.000 28 0 2001 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.400 None 1.000 16 1 1998 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.400 None 0.909 11 0 2014 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.400 None 1.000 1 0 2018 2018
Entrez Id: 8031
Gene Symbol: NCOA4
NCOA4
Q13772 nuclear receptor coactivator 4 Transcription factor 62 0.619 0.577 2.2E-06 0.380 None 1.000 9 0 1996 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.360 None 1.000 7 0 2002 2019
Entrez Id: 7170
Gene Symbol: TPM3
TPM3
P06753 tropomyosin 3 Cellular structure 297 0.490 0.808 6.7E-03 0.360 None 1.000 7 0 1997 2019
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 597 0.401 0.846 1.00 0.350 None 1.000 5 0 2002 2019
Entrez Id: 5909
Gene Symbol: RAP1GAP
RAP1GAP
P47736 RAP1 GTPase activating protein Enzyme modulator 63 0.626 0.500 0.84 0.350 None 1.000 5 1 2007 2012
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.340 None 1.000 5 1 2003 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.330 None 0.750 4 0 2009 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.330 None 1.000 4 0 2009 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.330 None 1.000 4 0 2014 2016
Entrez Id: 5168
Gene Symbol: ENPP2
ENPP2
Q13822 ectonucleotide pyrophosphatase/phosphodiesterase 2 Enzyme 95 0.582 0.769 2.8E-03 0.320 None 1.000 3 0 2004 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.310 None 1.000 2 1 2015 2019
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
P02778 C-X-C motif chemokine ligand 10 Signaling 631 0.378 0.885 0.37 0.310 None 1.000 2 0 2015 2019