Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 enzyme modulator 290 0.463 0.690 1.00 1.000 definitive 0.985 293 153 1994 2018
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 457 0.403 0.759 1.00 1.000 definitive 0.987 246 91 1990 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 901 0.323 0.897 0.47 0.310 1.000 2 0 1997 2006
Entrez Id: 1978
Gene Symbol: EIF4EBP1
EIF4EBP1
Q13541 eukaryotic translation initiation factor 4E binding protein 1 nucleic acid binding 119 0.529 0.793 0.21 0.220 1.000 3 0 2002 2014
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.100 0.978 47 0 2002 2018
Entrez Id: 54997
Gene Symbol: TESC
TESC
Q96BS2 tescalcin 44 0.636 0.586 0.38 0.100 1.000 17 0 1995 2016
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3
P55017 solute carrier family 12 member 3 99 0.564 0.690 4.7E-32 0.100 1.000 17 0 1995 2016
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
P98161 polycystin 1, transient receptor potential channel interacting 127 0.537 0.621 1.00 0.100 1.000 11 10 1995 2009
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma kinase; transferase 490 0.385 0.862 1.5E-06 0.100 0.909 11 0 2004 2015
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta kinase; transferase 487 0.386 0.862 1.00 0.100 0.909 11 0 2004 2015
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta kinase; transferase 468 0.389 0.862 1.00 0.100 0.909 11 0 2004 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.090 1.000 9 0 2004 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.070 0.857 7 0 2009 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.050 1.000 5 0 2004 2017
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
P20936 RAS p21 protein activator 1 enzyme modulator 126 0.534 0.655 1.00 0.050 1.000 5 0 1998 2009
Entrez Id: 54541
Gene Symbol: DDIT4
DDIT4
Q9NX09 DNA damage inducible transcript 4 38 0.648 0.517 7.3E-04 0.040 1.000 4 0 2005 2014
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 218 0.476 0.759 2.1E-12 0.040 1.000 4 0 2008 2010
Entrez Id: 6009
Gene Symbol: RHEB
RHEB
Q15382 Ras homolog, mTORC1 binding enzyme modulator 25 0.696 0.379 0.98 0.040 1.000 4 0 2003 2014
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase transferase 256 0.457 0.759 0.76 0.030 0.667 3 0 2004 2012
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 715 0.355 0.828 0.29 0.030 1.000 3 0 2007 2015
Entrez Id: 23373
Gene Symbol: CRTC1
CRTC1
Q6UUV9 CREB regulated transcription coactivator 1 transcription factor 65 0.602 0.621 0.43 0.030 1.000 3 0 2008 2013
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 611 0.365 0.931 1.00 0.030 1.000 3 0 2004 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.030 1.000 3 0 1996 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.030 1.000 3 0 1996 2006
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.030 1.000 3 0 2004 2014