Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7508
Gene Symbol: XPC
XPC
Q01831 XPC complex subunit, DNA damage recognition and repair factor nucleic acid binding 159 0.523 0.655 2.7E-11 0.900 0.957 29 4 1994 2017
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit nucleic acid binding 362 0.447 0.828 1.7E-20 0.700 0.896 74 7 1989 2016
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
P28715 ERCC excision repair 5, endonuclease 209 0.518 0.690 9.9E-13 0.700 1.000 20 2 1994 2016
Entrez Id: 2071
Gene Symbol: ERCC3
ERCC3
P19447 ERCC excision repair 3, TFIIH core complex helicase subunit hydrolase; nucleic acid binding 160 0.541 0.793 2.7E-11 0.600 0.939 34 1 1990 2016
Entrez Id: 5429
Gene Symbol: POLH
POLH
Q9Y253 DNA polymerase eta 36 0.667 0.414 3.3E-09 0.600 0.958 32 0 1999 2017
Entrez Id: 7507
Gene Symbol: XPA
XPA
P23025 XPA, DNA damage recognition and repair factor nucleic acid binding 139 0.551 0.655 7.2E-05 0.600 1.000 21 0 1991 2016
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4
Q92889 ERCC excision repair 4, endonuclease catalytic subunit nucleic acid binding 228 0.503 0.724 3.8E-12 0.600 1.000 11 2 1998 2016
Entrez Id: 1643
Gene Symbol: DDB2
DDB2
Q92466 damage specific DNA binding protein 2 nucleic acid binding 87 0.607 0.552 4.8E-06 0.590 1.000 11 0 1999 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.957 23 0 1987 2009
Entrez Id: 404672
Gene Symbol: GTF2H5
GTF2H5
Q6ZYL4 general transcription factor IIH subunit 5 55 0.621 0.690 4.5E-02 0.100 0.864 22 0 1994 2015
Entrez Id: 2965
Gene Symbol: GTF2H1
GTF2H1
P32780 general transcription factor IIH subunit 1 transcription factor 90 0.562 0.621 0.99 0.100 0.875 16 0 1993 2015
Entrez Id: 2966
Gene Symbol: GTF2H2
GTF2H2
Q13888 general transcription factor IIH subunit 2 transcription factor 24 0.690 0.414 8.4E-02 0.100 0.875 16 0 1993 2015
Entrez Id: 2967
Gene Symbol: GTF2H3
GTF2H3
Q13889 general transcription factor IIH subunit 3 nucleic acid binding; transcription factor 26 0.681 0.483 3.6E-08 0.100 0.875 16 0 1993 2015
Entrez Id: 7376
Gene Symbol: NR1H2
NR1H2
P55055 nuclear receptor subfamily 1 group H member 2 nucleic acid binding; receptor; transcription factor 94 0.552 0.552 0.42 0.100 1.000 16 0 2000 2016
Entrez Id: 2968
Gene Symbol: GTF2H4
GTF2H4
Q92759 general transcription factor IIH subunit 4 transcription factor 35 0.645 0.483 3.5E-07 0.100 0.867 15 1 1994 2015
Entrez Id: 10721
Gene Symbol: POLQ
POLQ
O75417 DNA polymerase theta hydrolase; nucleic acid binding; transferase 17 0.735 0.379 2.2E-80 0.100 0.923 13 0 1999 2015
Entrez Id: 100533467
Gene Symbol: BIVM-ERCC5
BIVM-ERCC5
BIVM-ERCC5 readthrough 12 0.762 0.241 6.6E-15 0.100 1 2 1994 1994
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase oxidoreductase 446 0.397 0.828 1.9E-10 0.080 1.000 8 0 1985 2008
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit nucleic acid binding 276 0.463 0.724 2.1E-07 0.060 0.667 6 0 1985 2014
Entrez Id: 284131
Gene Symbol: ENDOV
ENDOV
Q8N8Q3 endonuclease V 7 0.834 0.310 5.9E-09 0.050 1.000 5 0 1984 1993
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 264 0.449 0.828 4.8E-09 0.040 1.000 4 1 1994 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.030 1.000 3 0 2009 2014
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
P49917 DNA ligase 4 207 0.524 0.724 5.9E-06 0.030 1.000 3 0 1991 2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.030 1.000 3 0 1991 1994
Entrez Id: 442459
Gene Symbol: XRCC6P5
XRCC6P5
X-ray repair cross complementing 6 pseudogene 5 46 0.624 0.552 0.030 1.000 3 0 1991 2013