Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6469
Gene Symbol: SHH
SHH 		Q15465 sonic hedgehog signaling molecule 303 0.461 0.846 0.98 0.700 None 1.000 43 22 1994 2018
Entrez Id: 6496
Gene Symbol: SIX3
SIX3 		O95343 SIX homeobox 3 Transcription factor 117 0.560 0.692 0.95 0.700 strong 1.000 28 0 1996 2018
Entrez Id: 7050
Gene Symbol: TGIF1
TGIF1 		Q15583 TGFB induced factor homeobox 1 Enzyme 100 0.588 0.769 1.0E-02 0.700 strong 1.000 25 4 1995 2018
Entrez Id: 2736
Gene Symbol: GLI2
GLI2 		P10070 GLI family zinc finger 2 351 0.446 0.846 0.97 0.700 strong 1.000 17 0 2003 2019
Entrez Id: 4838
Gene Symbol: NODAL
NODAL 		Q96S42 nodal growth differentiation factor Signaling 89 0.588 0.731 0.97 0.620 limited 1.000 4 0 2008 2016
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2 		O95409 Zic family member 2 Transcription factor 125 0.556 0.769 0.97 0.500 None 1.000 37 3 1998 2020
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 604 0.398 0.885 1.00 0.460 strong 1.000 6 1 2002 2019
Entrez Id: 50937
Gene Symbol: CDON
CDON 		Q4KMG0 cell adhesion associated, oncogene regulated 80 0.601 0.731 2.1E-15 0.460 None 1.000 6 0 2003 2019
Entrez Id: 2253
Gene Symbol: FGF8
FGF8 		P55075 fibroblast growth factor 8 Signaling 212 0.507 0.769 0.68 0.450 strong 1.000 6 10 2010 2018
Entrez Id: 84976
Gene Symbol: DISP1
DISP1 		Q96F81 dispatched RND transporter family member 1 52 0.644 0.692 8.9E-08 0.430 strong 1.000 4 0 2007 2016
Entrez Id: 2619
Gene Symbol: GAS1
GAS1 		P54826 growth arrest specific 1 88 0.587 0.654 0.82 0.430 None 1.000 3 0 2007 2012
Entrez Id: 8928
Gene Symbol: FOXH1
FOXH1 		O75593 forkhead box H1 67 0.615 0.654 4.2E-02 0.420 limited 1.000 3 0 2008 2016
Entrez Id: 6997
Gene Symbol: TDGF1
TDGF1 		P13385 teratocarcinoma-derived growth factor 1 Calcium-binding protein 95 0.584 0.731 9.2E-11 0.400 None 1.000 1 0 2002 2002
Entrez Id: 57045
Gene Symbol: TWSG1
TWSG1 		Q9GZX9 twisted gastrulation BMP signaling modulator 1 57 0.621 0.692 6.1E-03 0.320 None 1.000 3 0 2004 2011
Entrez Id: 3244
Gene Symbol: HPE1
HPE1 		holoprosencephaly 1, alobar 3 0.890 0.115 0.310 None 1.000 1 0 1995 1995
Entrez Id: 4659
Gene Symbol: PPP1R12A
PPP1R12A 		O14974 protein phosphatase 1 regulatory subunit 12A 59 0.626 0.615 1.00 0.300 None 1.000 1 0 2020 2020
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1 		O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 54 0.650 0.577 2.5E-06 0.300 limited 0 0
Entrez Id: 23556
Gene Symbol: PIGN
PIGN 		O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 173 0.558 0.615 2.3E-21 0.200 None 0 0
Entrez Id: 80055
Gene Symbol: PGAP1
PGAP1 		Q75T13 post-GPI attachment to proteins inositol deacylase 1 Transporter 75 0.650 0.423 3.2E-08 0.200 None 0 0
Entrez Id: 1717
Gene Symbol: DHCR7
DHCR7 		Q9UBM7 7-dehydrocholesterol reductase Enzyme 266 0.500 0.846 3.9E-13 0.130 None 1.000 3 0 1996 2004
Entrez Id: 2737
Gene Symbol: GLI3
GLI3 		P10071 GLI family zinc finger 3 400 0.436 0.846 1.00 0.120 None 1.000 2 0 2012 2017
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.120 None 1.000 2 2 2016 2018
Entrez Id: 28514
Gene Symbol: DLL1
DLL1 		O00548 delta like canonical Notch ligand 1 212 0.492 0.808 1.00 0.110 None 1.000 1 0 2011 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 1.000 17 0 2001 2018
Entrez Id: 8785
Gene Symbol: MATN4
MATN4 		O95460 matrilin 4 Receptor 14 0.769 0.308 1.1E-08 0.100 None 0 1