Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
P52333 Janus kinase 3 Kinase 194 0.505 0.731 5.9E-06 0.700 strong 1.000 45 6 1995 2019
Entrez Id: 5896
Gene Symbol: RAG1
RAG1
P15918 recombination activating 1 Enzyme 209 0.509 0.769 2.8E-05 0.700 strong 0.952 42 5 2000 2019
Entrez Id: 5591
Gene Symbol: PRKDC
PRKDC
P78527 protein kinase, DNA-activated, catalytic subunit Kinase 131 0.540 0.808 1.00 0.700 strong 1.000 12 0 1995 2018
Entrez Id: 916
Gene Symbol: CD3E
CD3E
P07766 CD3e molecule 73 0.615 0.615 3.4E-04 0.620 definitive 1.000 8 0 1991 2014
Entrez Id: 7535
Gene Symbol: ZAP70
ZAP70
P43403 zeta chain of T cell receptor associated protein kinase 70 Kinase 212 0.497 0.769 0.88 0.600 None 0.846 13 1 1994 2017
Entrez Id: 915
Gene Symbol: CD3D
CD3D
P04234 CD3d molecule 67 0.626 0.577 8.6E-05 0.540 strong 1.000 5 0 2003 2014
Entrez Id: 100
Gene Symbol: ADA
ADA
P00813 adenosine deaminase Enzyme 379 0.440 0.885 2.9E-12 0.500 strong 0.991 111 9 1974 2019
Entrez Id: 5897
Gene Symbol: RAG2
RAG2
P55895 recombination activating 2 207 0.507 0.769 2.0E-02 0.500 strong 0.976 41 8 1994 2019
Entrez Id: 3561
Gene Symbol: IL2RG
IL2RG
P31785 interleukin 2 receptor subunit gamma Signaling 164 0.535 0.769 0.99 0.500 strong 0.971 35 3 1987 2020
Entrez Id: 64421
Gene Symbol: DCLRE1C
DCLRE1C
Q96SD1 DNA cross-link repair 1C 150 0.544 0.808 2.5E-07 0.500 strong 1.000 24 0 1995 2019
Entrez Id: 3575
Gene Symbol: IL7R
IL7R
P16871 interleukin 7 receptor Receptor 231 0.487 0.769 3.8E-07 0.500 strong 1.000 15 8 1998 2020
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
P49917 DNA ligase 4 293 0.478 0.846 4.2E-06 0.500 strong 1.000 13 0 2000 2019
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
P08575 protein tyrosine phosphatase receptor type C Enzyme 366 0.435 0.808 1.00 0.470 strong 1.000 7 0 2000 2018
Entrez Id: 204
Gene Symbol: AK2
AK2
P54819 adenylate kinase 2 Kinase 54 0.678 0.423 6.3E-05 0.400 None 1.000 2 0 2009 2009
Entrez Id: 919
Gene Symbol: CD247
CD247
P20963 CD247 molecule 140 0.539 0.731 1.7E-02 0.400 moderate 1.000 1 1 2015 2015
Entrez Id: 11151
Gene Symbol: CORO1A
CORO1A
P31146 coronin 1A Cellular structure 102 0.564 0.692 0.97 0.340 strong 1.000 4 0 2008 2016
Entrez Id: 50615
Gene Symbol: IL21R
IL21R
Q9HBE5 interleukin 21 receptor Receptor 110 0.550 0.731 1.00 0.310 strong 1.000 2 0 2003 2013
Entrez Id: 6899
Gene Symbol: TBX1
TBX1
O43435 T-box transcription factor 1 Transcription factor 417 0.433 0.808 0.84 0.300 moderate 1.000 1 0 2001 2001
Entrez Id: 7037
Gene Symbol: TFRC
TFRC
P02786 transferrin receptor Enzyme 359 0.437 0.885 7.0E-05 0.300 None 1.000 1 0 2016 2016
Entrez Id: 6948
Gene Symbol: TCN2
TCN2
P20062 transcobalamin 2 104 0.578 0.615 1.0E-06 0.300 strong 1.000 1 0 2009 2009
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.120 None 1.000 2 0 2000 2016
Entrez Id: 4522
Gene Symbol: MTHFD1
MTHFD1
P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 121 0.554 0.769 4.5E-03 0.120 None 1.000 2 0 2015 2017
Entrez Id: 55636
Gene Symbol: CHD7
CHD7
Q9P2D1 chromodomain helicase DNA binding protein 7 419 0.441 0.846 1.00 0.120 None 1.000 2 0 2008 2017
Entrez Id: 57217
Gene Symbol: TTC7A
TTC7A
Q9ULT0 tetratricopeptide repeat domain 7A 59 0.641 0.577 1.5E-31 0.120 None 1.000 2 0 2015 2018
Entrez Id: 64919
Gene Symbol: BCL11B
BCL11B
Q9C0K0 BAF chromatin remodeling complex subunit BCL11B Transcription factor 123 0.568 0.731 0.99 0.110 None 1.000 1 0 2016 2016