Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 326
Gene Symbol: AIRE
AIRE
O43918 autoimmune regulator 175 0.516 0.808 4.0E-12 0.400 None 1.000 18 0 1998 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.220 None 1.000 5 0 1991 2015
Entrez Id: 350
Gene Symbol: APOH
APOH
P02749 apolipoprotein H 121 0.563 0.769 1.6E-15 0.100 None 0.966 59 4 2001 2020
Entrez Id: 2152
Gene Symbol: F3
F3
P13726 coagulation factor III, tissue factor Receptor 456 0.415 0.846 1.9E-02 0.100 None 1.000 17 0 2003 2019
Entrez Id: 2821
Gene Symbol: GPI
GPI
P06744 glucose-6-phosphate isomerase Enzyme 218 0.491 0.769 2.8E-06 0.100 None 1.000 10 0 1999 2019
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.100 None 1.000 10 0 2001 2019
Entrez Id: 55190
Gene Symbol: NUDT11
NUDT11
Q96G61 nudix hydrolase 11 Enzyme 37 0.647 0.615 0.10 0.070 None 1.000 7 0 1998 2016
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.060 None 1.000 6 0 2001 2014
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.060 None 1.000 6 2 2009 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.060 None 1.000 6 1 2007 2019
Entrez Id: 170685
Gene Symbol: NUDT10
NUDT10
Q8NFP7 nudix hydrolase 10 Enzyme 23 0.705 0.423 0.11 0.050 None 1.000 5 0 2000 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.050 None 0.800 5 0 2015 2019
Entrez Id: 7804
Gene Symbol: LRP8
LRP8
Q14114 LDL receptor related protein 8 55 0.644 0.346 1.00 0.040 None 1.000 4 0 2015 2018
Entrez Id: 2153
Gene Symbol: F5
F5
P12259 coagulation factor V Enzyme 369 0.441 0.846 5.9E-15 0.040 None 1.000 4 0 2004 2014
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.040 None 1.000 4 0 2000 2013
Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
P08758 annexin A5 283 0.458 0.769 3.8E-15 0.040 None 1.000 4 0 2000 2017
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
Q8IUH3 RNA binding motif protein 45 557 0.383 0.846 2.1E-10 0.040 None 1.000 4 0 2001 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 1.000 4 0 2001 2019
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.030 None 1.000 3 2 2009 2018
Entrez Id: 1361
Gene Symbol: CPB2
CPB2
Q96IY4 carboxypeptidase B2 Enzyme 148 0.536 0.846 2.7E-17 0.030 None 1.000 3 0 2009 2017
Entrez Id: 10603
Gene Symbol: SH2B2
SH2B2
O14492 SH2B adaptor protein 2 59 0.623 0.731 1.5E-05 0.030 None 1.000 3 0 2018 2018
Entrez Id: 2149
Gene Symbol: F2R
F2R
P25116 coagulation factor II thrombin receptor G-protein coupled receptor 347 0.444 0.846 8.5E-03 0.030 None 1.000 3 0 2010 2017
Entrez Id: 354
Gene Symbol: KLK3
KLK3
P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.030 None 1.000 3 0 2018 2018
Entrez Id: 51284
Gene Symbol: TLR7
TLR7
Q9NYK1 toll like receptor 7 276 0.464 0.885 0.98 0.030 None 1.000 3 0 2011 2019
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 427 0.416 0.846 2.4E-02 0.030 None 1.000 3 0 2001 2014