Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
Q16647 prostaglandin I2 synthase 70 0.617 0.654 1.2E-09 0.630 limited < 0.001 3 2 2001 2003
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.600 None 0.932 146 3 1988 2020
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.600 None 0.941 51 7 1994 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.600 None 0.917 48 6 1995 2018
Entrez Id: 118
Gene Symbol: ADD1
ADD1
P35611 adducin 1 Cellular structure 67 0.612 0.615 0.99 0.400 None 0.944 36 4 1995 2017
Entrez Id: 2784
Gene Symbol: GNB3
GNB3
P16520 G protein subunit beta 3 Enzyme 192 0.518 0.808 3.3E-11 0.400 None 0.909 33 2 1998 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.330 None 1.000 3 0 1997 2001
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
O15539 regulator of G protein signaling 5 Enzyme modulator 52 0.647 0.423 5.3E-04 0.320 None 1.000 2 1 2009 2015
Entrez Id: 481
Gene Symbol: ATP1B1
ATP1B1
P05026 ATPase Na+/K+ transporting subunit beta 1 Transporter 34 0.700 0.462 1.00 0.310 None 1.000 1 0 2009 2009
Entrez Id: 1889
Gene Symbol: ECE1
ECE1
P42892 endothelin converting enzyme 1 Enzyme 157 0.541 0.769 0.96 0.310 None 1.000 1 0 2007 2007
Entrez Id: 50632
Gene Symbol: CALY
CALY
Q9NYX4 calcyon neuron specific vesicular protein 13 0.821 0.192 3.9E-02 0.300 None 1.000 1 0 2019 2019
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5
P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 179 0.511 0.846 6.3E-17 0.300 None 0 0
Entrez Id: 140628
Gene Symbol: GATA5
GATA5
Q9BWX5 GATA binding protein 5 101 0.578 0.615 0.28 0.200 None 1.000 1 0 2015 2015
Entrez Id: 7369
Gene Symbol: UMOD
UMOD
P07911 uromodulin 164 0.520 0.846 3.1E-17 0.110 None 1.000 1 1 2014 2014
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 0.927 110 3 1986 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.907 108 5 1992 2020
Entrez Id: 1585
Gene Symbol: CYP11B2
CYP11B2
P19099 cytochrome P450 family 11 subfamily B member 2 142 0.553 0.615 7.1E-19 0.100 None 0.949 39 4 1995 2018
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2
P80365 hydroxysteroid 11-beta dehydrogenase 2 Enzyme 163 0.532 0.808 0.12 0.100 None 0.778 18 3 1996 2017
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
Q9BYF1 angiotensin I converting enzyme 2 Enzyme 253 0.477 0.769 1.00 0.100 None 0.929 14 9 2002 2019
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
P07550 adrenoceptor beta 2 G-protein coupled receptor 387 0.442 0.923 0.53 0.100 None 1.000 14 5 1989 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.909 11 3 2005 2018
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3
P55017 solute carrier family 12 member 3 Transporter 252 0.493 0.808 3.0E-32 0.100 None 0.900 10 6 2004 2015
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
P08588 adrenoceptor beta 1 G-protein coupled receptor 130 0.555 0.769 2.9E-06 0.100 None 0.900 10 2 2002 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.100 None 1.000 10 0 1995 2019
Entrez Id: 101054525
Gene Symbol: PGR-AS1
PGR-AS1
PGR antisense RNA 1 172 0.514 0.808 0.100 None 0.900 10 0 1998 2014