Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.600 None 0.867 83 5 1993 2019
Entrez Id: 8074
Gene Symbol: FGF23
FGF23
Q9GZV9 fibroblast growth factor 23 Signaling 305 0.460 0.731 3.1E-02 0.100 None 0.952 42 0 2009 2020
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.400 None 1.000 38 2 1992 2019
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.600 None 0.941 34 0 1993 2018
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.100 None 0.952 21 1 1996 2010
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.100 None 0.917 12 0 2011 2020
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
P01160 natriuretic peptide A 217 0.505 0.769 5.5E-04 0.560 None 1.000 10 1 1997 2014
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
Q9BYF1 angiotensin I converting enzyme 2 Enzyme 253 0.477 0.769 1.00 0.280 None 1.000 9 2 2006 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.270 None 1.000 8 1 1997 2018
Entrez Id: 2784
Gene Symbol: GNB3
GNB3
P16520 G protein subunit beta 3 Enzyme 192 0.518 0.808 3.3E-11 0.080 None 1.000 8 1 2000 2006
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.550 None 1.000 8 0 1997 2016
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
P16860 natriuretic peptide B 193 0.513 0.808 9.9E-06 0.250 None 1.000 7 0 2006 2018
Entrez Id: 1585
Gene Symbol: CYP11B2
CYP11B2
P19099 cytochrome P450 family 11 subfamily B member 2 142 0.553 0.615 7.1E-19 0.070 None 1.000 7 1 2000 2018
Entrez Id: 2717
Gene Symbol: GLA
GLA
P06280 galactosidase alpha 190 0.537 0.769 1.00 0.170 None 1.000 7 2 2011 2019
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
P22455 fibroblast growth factor receptor 4 Kinase 220 0.490 0.769 7.2E-13 0.070 None 1.000 7 0 2015 2020
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
Q8TD31 coiled-coil alpha-helical rod protein 1 193 0.505 0.808 1.0E-16 0.070 None 1.000 7 0 2017 2019
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
P04278 sex hormone binding globulin 368 0.438 0.808 1.3E-06 0.070 None 1.000 7 0 2017 2019
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
Q13228 selenium binding protein 1 Immune response 214 0.493 0.846 3.2E-16 0.070 None 1.000 7 0 2017 2019
Entrez Id: 101054525
Gene Symbol: PGR-AS1
PGR-AS1
PGR antisense RNA 1 172 0.514 0.808 0.070 None 1.000 7 0 2002 2010
Entrez Id: 9197
Gene Symbol: SLC33A1
SLC33A1
O00400 solute carrier family 33 member 1 Transporter 170 0.529 0.769 9.9E-05 0.070 None 1.000 7 0 2002 2010
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.070 None 1.000 7 0 2002 2010
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
P08588 adrenoceptor beta 1 G-protein coupled receptor 130 0.555 0.769 2.9E-06 0.250 None 1.000 6 2 2002 2010
Entrez Id: 4607
Gene Symbol: MYBPC3
MYBPC3
Q14896 myosin binding protein C3 100 0.593 0.385 8.0E-11 0.150 None 1.000 6 4 2002 2019
Entrez Id: 23209
Gene Symbol: MLC1
MLC1
Q15049 modulator of VRAC current 1 Ion channel 87 0.585 0.769 3.2E-08 0.060 None 1.000 6 0 2000 2018
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.060 None 0.667 6 0 2003 2019