Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.400 0.843 75 1 1993 2016
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen enzyme modulator 451 0.406 0.862 3.9E-08 0.400 1.000 30 0 1992 2014
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin hydrolase; protease 373 0.423 0.759 2.1E-07 0.400 1.000 26 0 1993 2018
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
P01160 natriuretic peptide A 127 0.546 0.690 6.4E-04 0.370 0.800 9 0 1998 2014
Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
P50052 angiotensin II receptor type 2 receptor 110 0.554 0.621 8.2E-03 0.360 1.000 6 0 2003 2013
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 signaling molecule 419 0.417 0.828 0.46 0.340 1.000 6 0 1998 2007
Entrez Id: 5534
Gene Symbol: PPP3R1
PPP3R1
P63098 protein phosphatase 3 regulatory subunit B, alpha 16 0.743 0.276 0.42 0.320 1.000 3 0 2005 2008
Entrez Id: 1215
Gene Symbol: CMA1
CMA1
P23946 chymase 1 hydrolase; protease 80 0.575 0.517 9.4E-09 0.310 1.000 2 0 2004 2005
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
Q99988 growth differentiation factor 15 signaling molecule 174 0.496 0.621 2.9E-07 0.310 1.000 1 0 2009 2009
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
P23443 ribosomal protein S6 kinase B1 99 0.555 0.621 0.98 0.300 1 0 2009 2009
Entrez Id: 1158
Gene Symbol: CKM
CKM
P06732 creatine kinase, M-type kinase; transferase 11 0.815 0.241 8.2E-03 0.300 1 0 2001 2001
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.300 1 0 2009 2009
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 222 0.510 0.759 1.00 0.300 1 0 2001 2001
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
P02452 collagen type I alpha 1 chain 336 0.472 0.724 1.00 0.300 1 0 2001 2001
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor receptor; transcription factor 276 0.462 0.862 1.00 0.300 1 0 2004 2004
Entrez Id: 1152
Gene Symbol: CKB
CKB
P12277 creatine kinase B kinase; transferase 45 0.636 0.483 0.59 0.300 1 0 2001 2001
Entrez Id: 2548
Gene Symbol: GAA
GAA
P10253 glucosidase alpha, acid hydrolase 95 0.607 0.655 1.9E-17 0.300 1 0 2001 2001
Entrez Id: 5530
Gene Symbol: PPP3CA
PPP3CA
Q08209 protein phosphatase 3 catalytic subunit alpha 91 0.569 0.724 1.00 0.300 1 0 2008 2008
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
P13945 adrenoceptor beta 3 receptor 98 0.558 0.552 2.7E-07 0.300 1 0 2007 2007
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.300 1 0 2009 2009
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 signaling molecule 461 0.399 0.828 1.2E-03 0.300 1 0 2001 2001
Entrez Id: 58
Gene Symbol: ACTA1
ACTA1
P68133 actin, alpha 1, skeletal muscle cytoskeletal protein 151 0.590 0.586 9.5E-07 0.300 1 0 2000 2000
Entrez Id: 1839
Gene Symbol: HBEGF
HBEGF
Q99075 heparin binding EGF like growth factor signaling molecule 102 0.545 0.552 8.0E-02 0.300 1 0 1998 1998
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.300 1 0 2012 2012
Entrez Id: 2717
Gene Symbol: GLA
GLA
P06280 galactosidase alpha 135 0.588 0.621 1.00 0.140 1.000 4 0 2011 2015