Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.961 53 1 1993 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 1.000 14 0 1999 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 1.000 11 0 2003 2012
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide oxidoreductase 152 0.525 0.759 1.1E-06 0.400 2 1 2008 2016
Entrez Id: 11321
Gene Symbol: GPN1
GPN1
Q9HCN4 GPN-loop GTPase 1 nucleic acid binding 12 0.886 0.138 5.4E-05 0.400 1 1 2016 2016
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Q96KA5 CLPTM1 like lyase 60 0.602 0.517 5.7E-05 0.400 1 1 2016 2016
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CDKN2B antisense RNA 1 99 0.550 0.586 0.400 1 1 2016 2016
Entrez Id: 10319
Gene Symbol: LAMC3
LAMC3
Q9Y6N6 laminin subunit gamma 3 enzyme modulator; extracellular matrix protein; receptor 18 0.773 0.276 2.2E-23 0.400 1 2 2016 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.350 1.000 6 0 2012 2014
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.340 1.000 5 0 2004 2018
Entrez Id: 126
Gene Symbol: ADH1C
ADH1C
P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide oxidoreductase 88 0.567 0.655 0.330 1.000 4 0 1997 2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.330 1.000 4 0 1989 2014
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.330 0.667 3 2 2000 2014
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.320 1.000 4 0 1997 2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 signaling molecule 691 0.353 0.897 0.62 0.320 1.000 3 0 2011 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.320 1.000 3 0 2009 2011
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 457 0.403 0.759 1.00 0.320 1.000 3 0 1996 2008
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 437 0.404 0.862 2.9E-02 0.320 0.500 2 0 2014 2015
Entrez Id: 1834
Gene Symbol: DSPP
DSPP
Q9NZW4 dentin sialophosphoprotein 50 0.633 0.483 9.8E-07 0.320 1.000 2 0 2011 2015
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
Q92597 N-myc downstream regulated 1 hydrolase; protease 158 0.521 0.655 7.7E-03 0.310 1.000 2 0 2005 2013
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
P04083 annexin A1 178 0.498 0.828 1.5E-07 0.310 1.000 2 0 2005 2011
Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
P02511 crystallin alpha B 138 0.546 0.621 2.3E-02 0.310 1.000 2 3 2005 2012
Entrez Id: 23410
Gene Symbol: SIRT3
SIRT3
Q9NTG7 sirtuin 3 hydrolase; nucleic acid binding 73 0.598 0.586 1.7E-04 0.310 1.000 2 0 2011 2015
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 lyase; transferase 34 0.701 0.310 9.3E-14 0.310 1.000 1 0 2017 2017
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 196 0.489 0.690 2.3E-05 0.300 1 0 2012 2012