Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.100 1.000 16 1 1999 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.100 0.929 14 1 2010 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.100 1.000 12 0 1989 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.100 1.000 10 0 2006 2016
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 474 0.391 0.897 1.4E-02 0.100 1.000 10 0 2005 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.100 1.000 10 2 2007 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.090 1.000 9 0 2007 2016
Entrez Id: 3732
Gene Symbol: CD82
CD82
P27701 CD82 molecule 118 0.533 0.586 9.9E-09 0.070 0.857 7 0 1998 2016
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 564 0.373 0.931 0.49 0.070 1.000 7 0 1993 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.070 1.000 7 1 1998 2016
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
P16284 platelet and endothelial cell adhesion molecule 1 cell adhesion molecule 184 0.492 0.690 0.060 1.000 6 0 1995 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.060 1.000 6 0 2002 2016
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 enzyme modulator; membrane traffic protein; structural protein; transmembrane receptor regulatory/adaptor protein 421 0.416 0.828 7.2E-03 0.060 0.833 6 0 2004 2012
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.060 0.833 6 0 1999 2016
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
P07996 thrombospondin 1 288 0.448 0.759 1.00 0.060 1.000 6 0 1995 2010
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.050 1.000 5 0 2014 2016
Entrez Id: 10630
Gene Symbol: PDPN
PDPN
Q86YL7 podoplanin 98 0.554 0.690 3.5E-04 0.050 1.000 5 0 2007 2014
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 467 0.389 0.862 2.1E-07 0.050 1.000 5 0 1997 2016
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 481 0.391 0.862 1.0E-06 0.050 1.000 5 0 2003 2016
Entrez Id: 1822
Gene Symbol: ATN1
ATN1
P54259 atrophin 1 286 0.442 0.828 1.00 0.050 1.000 5 0 2012 2016
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 400 0.407 0.759 0.050 1.000 5 0 2008 2014
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1
P39060 collagen type XVIII alpha 1 chain 188 0.489 0.759 1.5E-09 0.050 1.000 5 0 2001 2016
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
P50281 matrix metallopeptidase 14 hydrolase; protease 240 0.466 0.724 1.00 0.050 1.000 5 0 1997 2017
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 signaling molecule 461 0.399 0.828 1.2E-03 0.050 0.800 5 0 2008 2016
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
P37275 zinc finger E-box binding homeobox 1 transcription factor 167 0.501 0.621 0.97 0.040 0.750 4 0 2009 2016