Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3145
Gene Symbol: HMBS
HMBS 		P08397 hydroxymethylbilane synthase Enzyme 140 0.559 0.731 0.95 1.000 strong 0.983 173 60 1974 2020
Entrez Id: 211
Gene Symbol: ALAS1
ALAS1 		P13196 5'-aminolevulinate synthase 1 Enzyme 27 0.705 0.462 0.11 0.080 None 1.000 8 0 2006 2020
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1 		P07477 serine protease 1 Enzyme 117 0.563 0.692 4.1E-11 0.040 None 1.000 4 0 2013 2017
Entrez Id: 9049
Gene Symbol: AIP
AIP 		O00170 aryl hydrocarbon receptor interacting protein Chaperone 216 0.517 0.769 0.36 0.040 None 1.000 4 0 1990 2019
Entrez Id: 5498
Gene Symbol: PPOX
PPOX 		P50336 protoporphyrinogen oxidase 53 0.678 0.500 2.8E-02 0.040 None 1.000 4 0 2002 2015
Entrez Id: 1990
Gene Symbol: CELA1
CELA1 		Q9UNI1 chymotrypsin like elastase 1 Enzyme 31 0.700 0.385 2.4E-04 0.030 None 1.000 3 0 2012 2018
Entrez Id: 7389
Gene Symbol: UROD
UROD 		P06132 uroporphyrinogen decarboxylase 166 0.521 0.769 1.3E-08 0.030 None 1.000 3 0 1989 2002
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1 		P00995 serine peptidase inhibitor Kazal type 1 216 0.492 0.808 0.31 0.030 None 1.000 3 0 2006 2014
Entrez Id: 643
Gene Symbol: CXCR5
CXCR5 		P32302 C-X-C motif chemokine receptor 5 G-protein coupled receptor 146 0.524 0.769 0.73 0.030 None 1.000 3 0 2017 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.030 None 1.000 3 0 2007 2010
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		P13716 aminolevulinate dehydratase Enzyme 135 0.556 0.615 5.6E-05 0.030 None 1.000 3 0 1981 1999
Entrez Id: 4055
Gene Symbol: LTBR
LTBR 		P36941 lymphotoxin beta receptor 78 0.592 0.692 0.31 0.020 None 1.000 2 0 2012 2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 2011 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.020 None 0.500 2 1 2009 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2007 2009
Entrez Id: 4049
Gene Symbol: LTA
LTA 		P01374 lymphotoxin alpha Signaling 353 0.434 0.885 0.20 0.020 None 1.000 2 0 2012 2014
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13 		P01562 interferon alpha 13 646 0.374 0.923 0.020 None 1.000 2 0 2017 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1 		P01562 interferon alpha 1 662 0.371 0.923 0.020 None 1.000 2 0 2017 2019
Entrez Id: 90865
Gene Symbol: IL33
IL33 		O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.020 None 1.000 2 0 2017 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.020 None 1.000 2 0 2009 2011
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.020 None 1.000 2 0 2011 2015
Entrez Id: 279
Gene Symbol: AMY2A
AMY2A 		P04746 amylase alpha 2A 21 0.716 0.423 8.5E-12 0.020 None 1.000 2 0 2009 2009
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		P01258 P06881 calcitonin related polypeptide alpha Signaling 467 0.416 0.923 1.6E-02 0.020 None 1.000 2 0 1989 1989
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1 		P04629 neurotrophic receptor tyrosine kinase 1 Kinase 443 0.422 0.808 2.0E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5037
Gene Symbol: PEBP1
PEBP1 		P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 181 0.500 0.808 9.2E-02 0.010 None 1.000 1 0 2018 2018