Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2
P62736 actin, alpha 2, smooth muscle, aorta cytoskeletal protein 131 0.540 0.690 0.93 0.700 strong 1.000 17 0 2007 2018
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 calcium-binding protein; cell adhesion molecule; extracellular matrix protein; signaling molecule 413 0.469 0.690 1.00 0.700 strong 1.000 12 37 1997 2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 kinase; receptor; transferase 361 0.437 0.793 0.15 0.600 strong 1.000 15 1 2003 2018
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
P61812 transforming growth factor beta 2 signaling molecule 226 0.480 0.793 1.00 0.550 strong 1.000 5 1 2012 2015
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.540 1.000 6 0 2006 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.520 1.000 4 0 2006 2010
Entrez Id: 8076
Gene Symbol: MFAP5
MFAP5
Q13361 microfibril associated protein 5 31 0.690 0.483 4.9E-03 0.410 moderate 1.000 1 0 2015 2015
Entrez Id: 5592
Gene Symbol: PRKG1
PRKG1
Q13976 protein kinase cGMP-dependent 1 94 0.575 0.724 1.00 0.410 strong 1.000 1 0 2013 2013
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 transcription factor 273 0.462 0.862 0.84 0.340 strong 1.000 4 0 2014 2015
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
P36897 transforming growth factor beta receptor 1 kinase; receptor; transferase 210 0.495 0.690 0.83 0.330 strong 1.000 3 0 2009 2018
Entrez Id: 4629
Gene Symbol: MYH11
MYH11
P35749 myosin heavy chain 11 99 0.567 0.483 0.88 0.330 strong 1.000 3 0 2006 2014
Entrez Id: 2006
Gene Symbol: ELN
ELN
P15502 elastin 412 0.455 0.828 2.3E-14 0.330 limited 1.000 3 0 2014 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.320 limited 1.000 2 0 2017 2018
Entrez Id: 4015
Gene Symbol: LOX
LOX
P28300 lysyl oxidase 187 0.488 0.793 0.99 0.320 strong 1.000 2 0 2014 2016
Entrez Id: 2201
Gene Symbol: FBN2
FBN2
P35556 fibrillin 2 calcium-binding protein; cell adhesion molecule; extracellular matrix protein; signaling molecule 134 0.541 0.690 1.00 0.310 limited 1.000 1 0 2013 2013
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 transcription factor 171 0.496 0.724 1.00 0.310 limited 1.000 1 0 2011 2011
Entrez Id: 2301
Gene Symbol: FOXE3
FOXE3
Q13461 forkhead box E3 nucleic acid binding; transcription factor 60 0.630 0.448 0.56 0.310 moderate 1.000 1 0 2016 2016
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.310 limited 1.000 1 0 2007 2007
Entrez Id: 633
Gene Symbol: BGN
BGN
P21810 biglycan 178 0.523 0.655 0.44 0.310 limited 1.000 1 0 2018 2018
Entrez Id: 4144
Gene Symbol: MAT2A
MAT2A
P31153 methionine adenosyltransferase 2A transferase 22 0.713 0.448 1.00 0.310 limited 1.000 1 0 2015 2015
Entrez Id: 10021
Gene Symbol: HCN4
HCN4
Q9Y3Q4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 26 0.690 0.172 1.00 0.300 limited 0 0
Entrez Id: 9968
Gene Symbol: MED12
MED12
Q93074 mediator complex subunit 12 nucleic acid binding; transcription factor 266 0.528 0.655 1.00 0.300 limited 0 0
Entrez Id: 6497
Gene Symbol: SKI
SKI
P12755 SKI proto-oncogene 202 0.545 0.690 1.00 0.300 limited 0 0
Entrez Id: 8985
Gene Symbol: PLOD3
PLOD3
O60568 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 oxidoreductase 61 0.685 0.517 3.0E-12 0.300 limited 0 0
Entrez Id: 81031
Gene Symbol: SLC2A10
SLC2A10
O95528 solute carrier family 2 member 10 transporter 99 0.594 0.621 2.4E-08 0.300 limited 0 0