Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.100 16 19 2008 2017
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 232 0.477 0.724 1.6E-16 0.100 14 27 2007 2017
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8
Q9H221 ATP binding cassette subfamily G member 8 transporter 95 0.584 0.448 2.0E-20 0.100 11 10 2009 2017
Entrez Id: 10452
Gene Symbol: TOMM40
TOMM40
O96008 translocase of outer mitochondrial membrane 40 membrane traffic protein 72 0.636 0.483 0.99 0.100 9 4 2008 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.100 8 3 2011 2017
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 69 0.584 0.621 1.00 0.100 8 11 2008 2015
Entrez Id: 57794
Gene Symbol: SUGP1
SUGP1
Q8IWZ8 SURP and G-patch domain containing 1 nucleic acid binding 54 0.642 0.517 0.99 0.100 7 3 2009 2017
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 hydrolase; protease 101 0.572 0.552 1.9E-17 0.100 7 24 2008 2017
Entrez Id: 3250
Gene Symbol: HPR
HPR
P00739 haptoglobin-related protein hydrolase; protease 47 0.633 0.483 6.8E-10 0.100 5 1 2010 2017
Entrez Id: 8701
Gene Symbol: DNAH11
DNAH11
Q96DT5 dynein axonemal heavy chain 11 cytoskeletal protein; hydrolase 35 0.690 0.345 8.8E-57 0.100 5 2 2009 2017
Entrez Id: 85440
Gene Symbol: DOCK7
DOCK7
Q96N67 dedicator of cytokinesis 7 enzyme modulator 38 0.727 0.345 1.0E-05 0.100 5 9 2010 2017
Entrez Id: 54957
Gene Symbol: TXNL4B
TXNL4B
Q9NX01 thioredoxin like 4B 10 0.886 0.069 4.2E-03 0.100 5 1 2010 2017
Entrez Id: 6484
Gene Symbol: ST3GAL4
ST3GAL4
Q11206 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 42 0.667 0.379 3.4E-02 0.100 4 3 2010 2017
Entrez Id: 9415
Gene Symbol: FADS2
FADS2
O95864 fatty acid desaturase 2 62 0.627 0.552 1.00 0.100 4 5 2009 2017
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A nucleic acid binding; transcription factor 187 0.515 0.621 0.96 0.100 4 2 2010 2017
Entrez Id: 2444
Gene Symbol: FRK
FRK
P42685 fyn related Src family tyrosine kinase 20 0.735 0.276 1.7E-12 0.100 4 3 2010 2017
Entrez Id: 57523
Gene Symbol: NYNRIN
NYNRIN
Q9P2P1 NYN domain and retroviral integrase containing nucleic acid binding 2 1.000 0.069 7.3E-10 0.100 4 2 2010 2017
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 nucleic acid binding 212 0.503 0.759 1.00 0.100 3 3 2011 2013
Entrez Id: 124989
Gene Symbol: EFCAB13
EFCAB13
Q8IY85 EF-hand calcium binding domain 13 8 0.886 0.103 5.3E-31 0.100 3 1 2010 2015
Entrez Id: 5339
Gene Symbol: PLEC
PLEC
Q15149 plectin cytoskeletal protein 160 0.569 0.655 8.4E-10 0.100 3 2 2010 2017
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.100 3 3 2012 2013
Entrez Id: 1463
Gene Symbol: NCAN
NCAN
O14594 neurocan extracellular matrix protein 21 0.727 0.345 5.0E-02 0.100 3 3 2012 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.100 3 2 2012 2014
Entrez Id: 55219
Gene Symbol: MACO1
MACO1
Q8N5G2 macoilin 1 7 1.000 0.034 0.100 3 2 2010 2017
Entrez Id: 64757
Gene Symbol: MARC1
MARC1
Q5VT66 mitochondrial amidoxime reducing component 1 5 0.928 0.069 4.0E-08 0.100 3 2 2010 2017