Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.300 None 1.000 5 0 1989 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.300 None 1.000 3 0 2001 2010
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.300 None 1.000 3 0 2000 2005
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.300 None 1.000 2 0 1997 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.300 None 1.000 2 0 1992 2009
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.300 None 1.000 2 0 2005 2011
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.300 None 1.000 2 0 2010 2011
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
P42229 signal transducer and activator of transcription 5A Nucleic acid binding 318 0.445 0.808 1.00 0.300 None 1.000 2 0 2010 2011
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.300 None 1.000 2 0 2009 2015
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.300 None 1.000 2 0 2010 2011
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
Q13228 selenium binding protein 1 Immune response 214 0.493 0.846 3.2E-16 0.300 None 1.000 2 0 2004 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.300 None 1.000 2 0 2011 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.300 None 1.000 2 0 1999 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.300 None 1.000 1 0 2007 2007
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.300 None 1.000 1 0 2015 2015
Entrez Id: 563
Gene Symbol: AZGP1
AZGP1
P25311 alpha-2-glycoprotein 1, zinc-binding 101 0.566 0.769 4.2E-06 0.300 None 1.000 1 0 2008 2008
Entrez Id: 5731
Gene Symbol: PTGER1
PTGER1
P34995 prostaglandin E receptor 1 G-protein coupled receptor 44 0.674 0.538 9.7E-04 0.300 None 1.000 1 0 2001 2001
Entrez Id: 56287
Gene Symbol: GKN1
GKN1
Q9NS71 gastrokine 1 55 0.628 0.615 1.1E-06 0.300 None 1.000 1 0 2004 2004
Entrez Id: 5915
Gene Symbol: RARB
RARB
P10826 retinoic acid receptor beta Nuclear receptor 254 0.478 0.846 1.00 0.300 None 1.000 1 0 2004 2004
Entrez Id: 59340
Gene Symbol: HRH4
HRH4
Q9H3N8 histamine receptor H4 G-protein coupled receptor 48 0.659 0.462 5.2E-08 0.300 None 1.000 1 0 2012 2012
Entrez Id: 58508
Gene Symbol: KMT2C
KMT2C
Q8NEZ4 lysine methyltransferase 2C 114 0.558 0.692 1.00 0.300 None 1.000 1 0 2012 2012
Entrez Id: 5617
Gene Symbol: PRL
PRL
P01236 prolactin Signaling 506 0.406 0.885 2.9E-07 0.300 None 1.000 1 0 1981 1981
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1
Q9P212 phospholipase C epsilon 1 Enzyme 114 0.572 0.654 5.7E-11 0.300 None 1.000 1 0 2010 2010
Entrez Id: 51292
Gene Symbol: GMPR2
GMPR2
Q9P2T1 guanosine monophosphate reductase 2 15 0.769 0.115 1.0E-08 0.300 None 1.000 1 0 2004 2004
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
Q9UBU3 ghrelin and obestatin prepropeptide 183 0.517 0.769 1.4E-11 0.300 None 1.000 1 0 2011 2011