Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.560 None 1.000 7 0 1995 2019
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.400 None 0.846 13 4 2006 2014
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.320 None 1.000 3 0 1997 2017
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.310 None 1.000 2 0 2014 2014
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.310 None 1.000 1 2 2009 2009
Entrez Id: 1540
Gene Symbol: CYLD
CYLD
Q9NQC7 CYLD lysine 63 deubiquitinase Enzyme 211 0.498 0.846 1.00 0.300 None 1.000 1 0 2014 2014
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 Epigenetic regulator 105 0.566 0.615 1.00 0.300 None 1.000 1 0 2014 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.923 13 0 2002 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 1.000 11 0 2016 2019
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.020 None 1.000 2 0 2014 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 1 2009 2014
Entrez Id: 2969
Gene Symbol: GTF2I
GTF2I
P78347 general transcription factor IIi 249 0.500 0.808 1.00 0.020 None 1.000 2 0 2017 2017
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.020 None 1.000 2 0 2014 2017
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
Q15116 programmed cell death 1 497 0.402 0.846 0.42 0.020 None 1.000 2 0 2019 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.020 None 1.000 2 0 2009 2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.020 None 1.000 2 0 2014 2016
Entrez Id: 10381
Gene Symbol: TUBB3
TUBB3
Q13509 tubulin beta 3 class III Cellular structure 259 0.486 0.808 2.6E-10 0.020 None 1.000 2 0 2017 2017
Entrez Id: 768
Gene Symbol: CA9
CA9
Q16790 carbonic anhydrase 9 226 0.483 0.731 1.3E-09 0.010 None 1.000 1 0 2019 2019
Entrez Id: 9536
Gene Symbol: PTGES
PTGES
O14684 prostaglandin E synthase 150 0.540 0.769 0.71 0.010 None 1.000 1 0 2006 2006
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 970
Gene Symbol: CD70
CD70
P32970 CD70 molecule 127 0.542 0.692 1.0E-02 0.010 None 1.000 1 0 2000 2000
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5269
Gene Symbol: SERPINB6
SERPINB6
P35237 serpin family B member 6 Enzyme modulator 128 0.547 0.769 1.1E-04 0.010 None 1.000 1 0 2018 2018