Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.600 None 0.973 369 4 1995 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 16 0 2004 2020
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
P07900 heat shock protein 90 alpha family class A member 1 Chaperone 455 0.411 0.923 0.86 0.320 None 1.000 3 0 2006 2017
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.300 None 1.000 1 0 2012 2012
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
P28908 TNF receptor superfamily member 8 301 0.444 0.808 0.86 0.100 None 0.958 190 0 1989 2020
Entrez Id: 4869
Gene Symbol: NPM1
NPM1
P06748 nucleophosmin 1 Chaperone 283 0.464 0.846 1.00 0.100 None 0.967 150 0 1994 2020
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 Kinase 224 0.493 0.769 9.7E-04 0.100 None 0.800 15 0 1997 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.929 14 1 1993 2019
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.100 None 0.786 14 0 1997 2018
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
Q15306 interferon regulatory factor 4 Transcription factor 203 0.491 0.769 0.86 0.090 None 1.000 9 0 2000 2019
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 344 0.442 0.885 6.0E-02 0.080 None 1.000 8 0 2012 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.080 None 1.000 8 0 1994 2019
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 264 0.467 0.769 0.86 0.080 None 1.000 8 0 2007 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.080 None 0.875 8 0 2000 2012
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.080 None 1.000 8 0 2011 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.070 None 0.857 7 0 1994 2014
Entrez Id: 56940
Gene Symbol: DUSP22
DUSP22
Q9NRW4 dual specificity phosphatase 22 40 0.659 0.615 9.3E-03 0.070 None 1.000 7 0 2011 2020
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.070 None 1.000 7 0 2001 2005
Entrez Id: 57599
Gene Symbol: WDR48
WDR48
Q8TAF3 WD repeat domain 48 57 0.628 0.615 1.00 0.060 None 0.833 6 0 1996 2002
Entrez Id: 8161
Gene Symbol: COIL
COIL
P38432 coilin Nucleic acid binding 51 0.617 0.654 9.4E-03 0.060 None 0.833 6 0 1996 2002
Entrez Id: 3554
Gene Symbol: IL1R1
IL1R1
P14778 interleukin 1 receptor type 1 Receptor 184 0.509 0.769 0.15 0.060 None 0.833 6 0 1996 2002
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.050 None 1.000 5 0 1998 2018
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
P29475 nitric oxide synthase 1 521 0.408 0.885 1.00 0.050 None 1.000 5 0 1998 2018
Entrez Id: 3727
Gene Symbol: JUND
JUND
P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 242 0.475 0.808 0.70 0.050 None 1.000 5 0 2015 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.050 None 1.000 5 0 1998 2011