Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.800 0.950 46 20 1992 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 505 0.399 0.828 4.7E-02 0.500 0.933 17 0 1993 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.430 1.000 5 5 2005 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.420 1.000 4 2 2009 2016
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor 373 0.433 0.828 0.99 0.350 1.000 6 0 2011 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.340 1.000 4 0 2009 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.320 1.000 3 0 1998 2014
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
O00255 menin 1 273 0.463 0.724 1.00 0.320 1.000 3 0 2011 2014
Entrez Id: 6240
Gene Symbol: RRM1
RRM1
P23921 ribonucleotide reductase catalytic subunit M1 oxidoreductase 71 0.584 0.483 1.00 0.320 1.000 2 0 2012 2015
Entrez Id: 84133
Gene Symbol: ZNRF3
ZNRF3
Q9ULT6 zinc and ring finger 3 22 0.752 0.310 0.99 0.310 1.000 2 0 2014 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.310 1.000 2 0 1991 2002
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.310 1.000 2 0 2014 2015
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
P11388 DNA topoisomerase II alpha 122 0.542 0.621 1.00 0.310 1.000 1 0 2013 2013
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 hydrolase; protease 186 0.488 0.586 0.99 0.300 1 0 2015 2015
Entrez Id: 9968
Gene Symbol: MED12
MED12
Q93074 mediator complex subunit 12 nucleic acid binding; transcription factor 266 0.528 0.655 1.00 0.300 1 0 2014 2014
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 nucleic acid binding; transcription factor 264 0.467 0.828 1.00 0.300 1 0 2014 2014
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
P09486 secreted protein acidic and cysteine rich cell adhesion molecule; extracellular matrix protein; signaling molecule 251 0.466 0.793 0.88 0.300 1 0 2012 2012
Entrez Id: 1616
Gene Symbol: DAXX
DAXX
Q9UER7 death domain associated protein 62 0.602 0.552 9.3E-02 0.300 1 0 2014 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase enzyme modulator 477 0.420 0.690 0.53 0.120 1.000 3 3 1989 2016
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
P49918 cyclin dependent kinase inhibitor 1C 244 0.479 0.724 0.82 0.110 1.000 1 0 1997 1997
Entrez Id: 283120
Gene Symbol: H19
H19
H19, imprinted maternally expressed transcript 196 0.525 0.759 0.110 1.000 1 0 2002 2002
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.110 1.000 1 0 1992 1992
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.100 1 3 2016 2016
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 394 0.443 0.793 0.71 0.100 1 2 2016 2016
Entrez Id: 3020
Gene Symbol: H3F3A
H3F3A
P84243 H3 histone family member 3A nucleic acid binding 30 0.667 0.310 0.13 0.100 1 1 2016 2016