Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 394 0.443 0.793 0.71 0.450 1.000 7 1 2004 2015
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4
P56524 histone deacetylase 4 133 0.558 0.655 1.00 0.440 1.000 5 0 2010 2015
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.400 1 0 2012 2012
Entrez Id: 4920
Gene Symbol: ROR2
ROR2
Q01974 receptor tyrosine kinase like orphan receptor 2 209 0.534 0.690 7.7E-04 0.160 0.667 6 1 2002 2011
Entrez Id: 3239
Gene Symbol: HOXD13
HOXD13
P35453 homeobox D13 167 0.541 0.621 5.3E-02 0.150 1.000 5 0 2003 2016
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
P12272 parathyroid hormone like hormone 238 0.472 0.793 0.83 0.150 1.000 5 0 2010 2016
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 calcium-binding protein; cell adhesion molecule; extracellular matrix protein; signaling molecule 413 0.469 0.690 1.00 0.140 1.000 4 0 2012 2017
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
P43026 growth differentiation factor 5 signaling molecule 217 0.557 0.517 0.68 0.130 1.000 3 0 2006 2014
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
P02458 collagen type II alpha 1 chain 443 0.474 0.724 1.00 0.130 1.000 3 0 1994 2005
Entrez Id: 3549
Gene Symbol: IHH
IHH
Q14623 indian hedgehog 136 0.572 0.621 0.33 0.130 0.667 3 0 2005 2011
Entrez Id: 22856
Gene Symbol: CHSY1
CHSY1
Q86X52 chondroitin sulfate synthase 1 transferase 43 0.713 0.414 0.91 0.120 1.000 2 0 2011 2012
Entrez Id: 54496
Gene Symbol: PRMT7
PRMT7
Q9NVM4 protein arginine methyltransferase 7 transferase 71 0.672 0.379 5.6E-15 0.110 1.000 2 1 2015 2017
Entrez Id: 7227
Gene Symbol: TRPS1
TRPS1
Q9UHF7 transcriptional repressor GATA binding 1 177 0.594 0.552 1.00 0.110 1.000 2 1 2001 2015
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
Q14432 phosphodiesterase 3A 28 0.752 0.345 6.4E-03 0.110 1.000 1 0 2015 2015
Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D
Q08499 phosphodiesterase 4D 168 0.572 0.690 1.00 0.110 1.000 1 0 2018 2018
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 558 0.417 0.759 1.8E-05 0.110 1.000 1 0 1998 1998
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 386 0.435 0.759 1.00 0.110 1.000 1 0 2007 2007
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 nucleic acid binding; transcription factor 292 0.464 0.759 0.36 0.110 1.000 1 0 1997 1997
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 349 0.466 0.690 1.00 0.110 1.000 1 0 2014 2014
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 727 0.406 0.724 1.00 0.110 1.000 1 0 2008 2008
Entrez Id: 3209
Gene Symbol: HOXA13
HOXA13
P31271 homeobox A13 75 0.611 0.414 0.96 0.110 1.000 1 0 2005 2005
Entrez Id: 658
Gene Symbol: BMPR1B
BMPR1B
O00238 bone morphogenetic protein receptor type 1B kinase; receptor; transferase 126 0.604 0.483 1.00 0.110 1.000 1 0 2016 2016
Entrez Id: 9241
Gene Symbol: NOG
NOG
Q13253 noggin 160 0.558 0.621 0.89 0.110 1.000 1 1 2012 2012
Entrez Id: 25836
Gene Symbol: NIPBL
NIPBL
Q6KC79 NIPBL, cohesin loading factor nucleic acid binding 188 0.557 0.690 1.00 0.100 1 1 2015 2015
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
Q9UMX1 SUFU negative regulator of hedgehog signaling 132 0.565 0.621 1.00 0.100 0 0