Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.800 0.967 427 24 1989 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.700 0.935 171 3 1990 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.650 0.800 5 2 2014 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.600 0.976 804 9 1988 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.600 0.978 46 1 2002 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.600 1.000 36 1 2003 2017
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 398 0.406 0.828 7.1E-02 0.600 0.788 34 3 1999 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.600 1.000 30 1 1998 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.600 1.000 29 2 2003 2018
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor 293 0.464 0.586 5.5E-02 0.520 1.000 3 1 1994 2005
Entrez Id: 5519
Gene Symbol: PPP2R1B
PPP2R1B
P30154 protein phosphatase 2 scaffold subunit Abeta hydrolase; phosphatase 23 0.696 0.276 2.9E-15 0.520 1.000 2 3 2000 2000
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 hydrolase; protease 186 0.488 0.586 0.99 0.510 1.000 2 0 2016 2016
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
Q96BI1 solute carrier family 22 member 18 50 0.621 0.483 6.0E-06 0.500 0 0
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.400 0.907 121 1 1993 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 0.932 90 2 1994 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 0.987 77 1 1989 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.400 0.970 66 1 2000 2018
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad 277 0.450 0.828 2.9E-02 0.400 1.000 52 0 1996 2018
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 356 0.419 0.862 1.3E-04 0.400 0.920 50 0 1997 2017
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.400 0.976 43 7 2001 2016
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 enzyme modulator 307 0.429 0.793 3.7E-06 0.400 0.854 42 1 2001 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.400 0.949 41 1 2003 2017
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
P30532 cholinergic receptor nicotinic alpha 5 subunit receptor; transporter 81 0.598 0.414 1.8E-06 0.400 0.950 41 6 2008 2016
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
P32297 cholinergic receptor nicotinic alpha 3 subunit receptor; transporter 84 0.584 0.448 1.2E-07 0.400 1.000 40 13 2008 2017
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 218 0.476 0.759 2.1E-12 0.400 0.946 39 3 1998 2016