Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 262
Gene Symbol: AMD1
AMD1
P17707 adenosylmethionine decarboxylase 1 Enzyme 84 0.593 0.577 0.98 0.100 None 1.000 26 0 2007 2020
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
adenosylmethionine decarboxylase 1 pseudogene 2 71 0.608 0.538 0.100 None 1.000 24 0 2007 2020
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 325 0.445 0.923 0.63 0.500 None 0.905 21 0 1997 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 16 0 2012 2020
Entrez Id: 7263
Gene Symbol: TST
TST
Q16762 thiosulfate sulfurtransferase Enzyme 91 0.588 0.654 7.9E-05 0.100 None 1.000 14 0 1993 2014
Entrez Id: 7439
Gene Symbol: BEST1
BEST1
O76090 bestrophin 1 Ion channel 292 0.465 0.885 1.8E-12 0.200 None 0.846 13 0 1998 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 11 0 2007 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.080 None 1.000 8 0 2014 2019
Entrez Id: 2273
Gene Symbol: FHL1
FHL1
Q13642 four and a half LIM domains 1 195 0.532 0.731 0.97 0.080 None 1.000 8 0 2007 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.080 None 1.000 8 0 2013 2019
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.080 None 0.750 8 0 2010 2019
Entrez Id: 1001
Gene Symbol: CDH3
CDH3
P22223 cadherin 3 119 0.560 0.615 2.8E-10 0.170 None 1.000 7 0 2001 2017
Entrez Id: 5630
Gene Symbol: PRPH
PRPH
P41219 peripherin 73 0.623 0.462 4.8E-14 0.060 None 1.000 6 0 1994 2011
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.060 None 0.833 6 0 2006 2016
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.060 None 1.000 6 0 2003 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.060 None 1.000 6 0 1998 2018
Entrez Id: 27259
Gene Symbol: HPLH1
HPLH1
hemophagocytic lymphohistiocytosis 1 22 0.695 0.538 0.060 None 1.000 6 0 2007 2018
Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
P14550 aldo-keto reductase family 1 member A1 Enzyme 185 0.510 0.846 6.7E-07 0.050 None 0.800 5 0 2004 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.050 None 1.000 5 0 2009 2017
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.340 None 1.000 5 0 2013 2019
Entrez Id: 80210
Gene Symbol: ARMC9
ARMC9
Q7Z3E5 armadillo repeat containing 9 80 0.612 0.731 6.2E-17 0.050 None 0.800 5 0 2004 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.050 None 0.800 5 0 2002 2019
Entrez Id: 4658
Gene Symbol: MYP2
MYP2
myopia 2 (high grade, autosomal dominant) 38 0.659 0.308 0.040 None 1.000 4 0 2011 2018
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
P09038 fibroblast growth factor 2 Signaling 635 0.383 0.923 1.8E-02 0.040 None 1.000 4 0 2001 2017
Entrez Id: 5228
Gene Symbol: PGF
PGF
P49763 placental growth factor Signaling 288 0.460 0.846 0.13 0.040 None 1.000 4 0 2018 2019