Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 387715
Gene Symbol: ARMS2
ARMS2
P0C7Q2 age-related maculopathy susceptibility 2 36 0.670 0.308 5.2E-04 0.700 limited 0.951 182 8 2005 2019
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
P78363 ATP binding cassette subfamily A member 4 Transporter 227 0.493 0.769 5.3E-48 0.700 strong 0.957 70 7 1997 2019
Entrez Id: 629
Gene Symbol: CFB
CFB
P00751 complement factor B 139 0.532 0.769 4.7E-16 0.700 limited 0.966 58 12 2006 2019
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.700 limited 1.000 36 12 2007 2020
Entrez Id: 717
Gene Symbol: C2
C2
P06681 complement C2 71 0.617 0.692 1.3E-16 0.680 limited 1.000 13 9 2006 2018
Entrez Id: 3075
Gene Symbol: CFH
CFH
P08603 complement factor H 393 0.441 0.885 0.86 0.500 None 0.961 486 85 2005 2019
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.500 limited 0.940 133 12 2006 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.500 None 0.902 61 4 1998 2019
Entrez Id: 3426
Gene Symbol: CFI
CFI
P05156 complement factor I 133 0.569 0.731 3.5E-08 0.500 None 0.960 25 4 2009 2019
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 325 0.445 0.923 0.63 0.500 None 0.905 21 0 1997 2019
Entrez Id: 10878
Gene Symbol: CFHR3
CFHR3
Q02985 complement factor H related 3 55 0.663 0.462 1.7E-11 0.500 moderate 1.000 17 2 2006 2019
Entrez Id: 3078
Gene Symbol: CFHR1
CFHR1
Q03591 complement factor H related 1 90 0.588 0.615 2.6E-08 0.500 moderate 1.000 16 4 2006 2017
Entrez Id: 83872
Gene Symbol: HMCN1
HMCN1
Q96RW7 hemicentin 1 28 0.736 0.577 3.6E-38 0.500 limited 0.846 13 1 2003 2015
Entrez Id: 6103
Gene Symbol: RPGR
RPGR
Q92834 retinitis pigmentosa GTPase regulator 167 0.536 0.692 1.00 0.430 None 1.000 3 0 2002 2019
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
Q92496 complement factor H related 4 11 0.839 0.346 2.4E-18 0.420 moderate 1.000 8 12 2008 2018
Entrez Id: 23539
Gene Symbol: SLC16A8
SLC16A8
O95907 solute carrier family 16 member 8 Transporter 13 0.760 0.231 9.0E-03 0.420 None 1.000 4 1 2013 2018
Entrez Id: 735
Gene Symbol: C9
C9
P02748 complement C9 62 0.619 0.692 1.6E-24 0.420 None 1.000 4 4 2013 2018
Entrez Id: 3080
Gene Symbol: CFHR2
CFHR2
P36980 complement factor H related 2 12 0.769 0.346 1.5E-08 0.410 limited 1.000 2 4 2008 2013
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 0.971 174 12 2000 2020
Entrez Id: 6017
Gene Symbol: RLBP1
RLBP1
P12271 retinaldehyde binding protein 1 Transporter 67 0.644 0.500 1.1E-05 0.400 None 1.000 1 0 2019 2019
Entrez Id: 84839
Gene Symbol: RAX2
RAX2
Q96IS3 retina and anterior neural fold homeobox 2 21 0.780 0.192 8.3E-03 0.400 strong 0 0
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.370 None 0.571 7 4 2005 2019
Entrez Id: 114902
Gene Symbol: C1QTNF5
C1QTNF5
Q9BXJ0 C1q and TNF related 5 45 0.663 0.346 0.84 0.370 None 1.000 7 1 2003 2018
Entrez Id: 10516
Gene Symbol: FBLN5
FBLN5
Q9UBX5 fibulin 5 Calcium-binding protein 150 0.546 0.692 1.00 0.370 limited 0.857 7 5 2004 2016
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.340 None 1.000 5 0 2013 2019