Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3075
Gene Symbol: CFH
CFH
P08603 complement factor H 225 0.478 0.793 0.96 0.500 0.963 413 78 2005 2018
Entrez Id: 387715
Gene Symbol: ARMS2
ARMS2
P0C7Q2 age-related maculopathy susceptibility 2 30 0.681 0.276 4.3E-04 0.500 0.973 191 6 2006 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.500 0.940 51 3 1998 2017
Entrez Id: 629
Gene Symbol: CFB
CFB
P00751 complement factor B 71 0.588 0.724 2.5E-16 0.500 0.952 48 11 2006 2016
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 defense/immunity protein; enzyme modulator; signaling molecule 187 0.484 0.828 0.94 0.500 1.000 31 7 2007 2018
Entrez Id: 3426
Gene Symbol: CFI
CFI
P05156 complement factor I 57 0.633 0.517 2.6E-08 0.500 0.941 19 3 2009 2017
Entrez Id: 717
Gene Symbol: C2
C2
P06681 complement C2 41 0.645 0.552 5.0E-17 0.470 1.000 12 11 2006 2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.970 102 8 2000 2018
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
P78363 ATP binding cassette subfamily A member 4 transporter 180 0.520 0.793 5.8E-47 0.400 0.969 68 4 1997 2018
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
P35625 TIMP metallopeptidase inhibitor 3 enzyme modulator 207 0.473 0.793 0.66 0.400 0.692 14 0 1997 2016
Entrez Id: 23539
Gene Symbol: SLC16A8
SLC16A8
O95907 solute carrier family 16 member 8 transporter 8 0.785 0.138 9.0E-03 0.400 2 1 2013 2016
Entrez Id: 735
Gene Symbol: C9
C9
P02748 complement C9 36 0.652 0.517 1.6E-24 0.400 2 1 2014 2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.360 0.667 6 2 2005 2016
Entrez Id: 114902
Gene Symbol: C1QTNF5
C1QTNF5
Q9BXJ0 C1q and TNF related 5 18 0.752 0.172 0.84 0.360 1.000 6 1 2004 2014
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A
O00220 TNF receptor superfamily member 10a 118 0.536 0.655 4.5E-14 0.330 0.667 3 1 2011 2014
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6
P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 281 0.507 0.690 8.1E-22 0.330 1.000 3 1 2006 2015
Entrez Id: 6103
Gene Symbol: RPGR
RPGR
Q92834 retinitis pigmentosa GTPase regulator 107 0.577 0.621 1.00 0.320 1.000 2 0 2003 2009
Entrez Id: 64802
Gene Symbol: NMNAT1
NMNAT1
Q9HAN9 nicotinamide nucleotide adenylyltransferase 1 transferase 37 0.696 0.207 3.2E-02 0.300 1 0 2012 2012
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 273 0.490 0.828 1.0E-02 0.300 1 0 2014 2014
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
P41597 C-C motif chemokine receptor 2 225 0.471 0.793 2.5E-02 0.250 1.000 5 0 2008 2014
Entrez Id: 4179
Gene Symbol: CD46
CD46
P15529 CD46 molecule 122 0.529 0.828 4.6E-07 0.230 1.000 3 0 2011 2015
Entrez Id: 56890
Gene Symbol: MDM1
MDM1
Q8TC05 Mdm1 nuclear protein 1 1.000 0.034 4.0E-12 0.210 < 0.001 1 0 2009 2009
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
Q92743 HtrA serine peptidase 1 chaperone; hydrolase; protease 106 0.572 0.621 5.7E-04 0.200 0.947 88 13 2006 2018
Entrez Id: 3078
Gene Symbol: CFHR1
CFHR1
Q03591 complement factor H related 1 33 0.652 0.379 3.1E-08 0.200 1.000 13 3 2006 2016
Entrez Id: 10878
Gene Symbol: CFHR3
CFHR3
Q02985 complement factor H related 3 16 0.735 0.241 1.8E-11 0.200 1.000 12 1 2006 2014