Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.400 None 0.956 68 0 1990 2019
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.400 None 1.000 49 2 1999 2020
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 314 0.454 0.808 0.89 0.400 None 0.962 26 1 1989 2019
Entrez Id: 5015
Gene Symbol: OTX2
OTX2
P32243 orthodenticle homeobox 2 Transcription factor 200 0.514 0.808 0.92 0.400 None 1.000 25 0 1999 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.400 None 0.960 25 0 2000 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 14 0 2008 2019
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
Q9UMX1 SUFU negative regulator of hedgehog signaling 272 0.493 0.769 1.00 0.400 None 1.000 14 0 2004 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.400 None 1.000 12 0 2005 2018
Entrez Id: 474
Gene Symbol: ATOH1
ATOH1
Q92858 atonal bHLH transcription factor 1 Enzyme 53 0.633 0.500 1.8E-02 0.390 None 1.000 9 0 2008 2019
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
Q00534 cyclin dependent kinase 6 Kinase 266 0.471 0.731 0.98 0.380 None 1.000 10 0 2005 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.380 None 1.000 9 0 1995 2018
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.380 None 1.000 9 0 1995 2020
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.360 None 1.000 6 0 2002 2011
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.350 None 1.000 6 0 2009 2017
Entrez Id: 3090
Gene Symbol: HIC1
HIC1
Q14526 HIC ZBTB transcriptional repressor 1 Transcription factor 163 0.522 0.615 0.13 0.350 None 1.000 5 0 2002 2008
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
P26358 DNA methyltransferase 1 Epigenetic regulator 496 0.406 0.885 1.00 0.340 None 1.000 5 0 2009 2018
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
O60885 bromodomain containing 4 Epigenetic regulator 335 0.446 0.885 1.00 0.340 None 1.000 5 0 2013 2019
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.340 None 1.000 5 0 2001 2015
Entrez Id: 23532
Gene Symbol: PRAME
PRAME
P78395 preferentially expressed antigen in melanoma 134 0.531 0.577 2.4E-07 0.330 None 1.000 4 0 2003 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.330 None 1.000 3 2 2003 2011
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
P26447 S100 calcium binding protein A4 Calcium-binding protein 308 0.448 0.769 6.2E-03 0.310 None 1.000 2 0 2003 2007
Entrez Id: 4610
Gene Symbol: MYCL
MYCL
P12524 MYCL proto-oncogene, bHLH transcription factor Transcription factor 79 0.599 0.731 0.12 0.310 None 1.000 2 0 2009 2012
Entrez Id: 7409
Gene Symbol: VAV1
VAV1
P15498 vav guanine nucleotide exchange factor 1 103 0.556 0.769 1.00 0.310 None 1.000 2 0 2009 2015
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
P60903 S100 calcium binding protein A10 Calcium-binding protein 150 0.528 0.769 0.17 0.310 None 1.000 1 0 2007 2007
Entrez Id: 6277
Gene Symbol: S100A6
S100A6
P06703 S100 calcium binding protein A6 Calcium-binding protein 168 0.510 0.808 0.18 0.310 None 1.000 1 0 2007 2007