Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase 274 0.448 0.724 3.5E-06 0.320 1.000 3 0 2012 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.100 1.000 38 0 1989 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.100 1.000 11 0 2007 2017
Entrez Id: 389
Gene Symbol: RHOC
RHOC
P08134 ras homolog family member C enzyme modulator 36 0.656 0.310 0.76 0.100 1.000 10 0 1999 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.060 1.000 6 0 2001 2017
Entrez Id: 331
Gene Symbol: XIAP
XIAP
P98170 X-linked inhibitor of apoptosis enzyme modulator 184 0.499 0.759 0.93 0.050 1.000 5 0 2008 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.050 0.800 5 0 1992 2010
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor nucleic acid binding; receptor; transcription factor 230 0.467 0.690 7.2E-02 0.050 1.000 5 0 1990 2011
Entrez Id: 8838
Gene Symbol: WISP3
WISP3
O95389 WNT1 inducible signaling pathway protein 3 signaling molecule 80 0.627 0.448 4.3E-04 0.050 0.800 5 0 2002 2009
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 611 0.365 0.931 1.00 0.040 1.000 4 0 2005 2013
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 494 0.386 0.897 1.0E-16 0.040 1.000 4 0 1989 2016
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 enzyme modulator; membrane traffic protein; structural protein; transmembrane receptor regulatory/adaptor protein 421 0.416 0.828 7.2E-03 0.030 1.000 3 0 2006 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.030 1.000 3 0 1989 2016
Entrez Id: 1981
Gene Symbol: EIF4G1
EIF4G1
Q04637 eukaryotic translation initiation factor 4 gamma 1 nucleic acid binding 51 0.630 0.586 1.00 0.020 1.000 2 0 2009 2010
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 222 0.473 0.690 6.7E-15 0.020 1.000 2 0 2014 2016
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 336 0.429 0.828 9.3E-02 0.020 1.000 2 0 2002 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.020 1.000 2 0 2002 2010
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.020 1.000 2 0 2012 2013
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.020 1.000 2 0 2008 2010
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.020 1.000 2 0 2014 2016
Entrez Id: 5747
Gene Symbol: PTK2
PTK2
Q05397 protein tyrosine kinase 2 112 0.545 0.655 1.00 0.020 1.000 2 0 2014 2016
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 474 0.391 0.897 1.4E-02 0.010 1.000 1 0 2007 2007
Entrez Id: 7471
Gene Symbol: WNT1
WNT1
P04628 Wnt family member 1 signaling molecule 113 0.555 0.655 0.25 0.010 1.000 1 0 2008 2008
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 nucleic acid binding 212 0.503 0.759 1.00 0.010 1.000 1 0 2016 2016
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor nucleic acid binding; receptor; transcription factor 533 0.390 0.793 6.3E-05 0.010 1.000 1 0 2013 2013