Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.400 None 0.985 66 0 1990 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.967 60 3 1991 2019
Entrez Id: 6469
Gene Symbol: SHH
SHH 		Q15465 sonic hedgehog signaling molecule 303 0.461 0.846 0.98 0.100 None 0.982 56 0 2000 2019
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 604 0.398 0.885 1.00 0.400 None 1.000 48 2 1999 2020
Entrez Id: 2735
Gene Symbol: GLI1
GLI1 		P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.100 None 1.000 27 0 2005 2019
Entrez Id: 4613
Gene Symbol: MYCN
MYCN 		P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 314 0.454 0.808 0.89 0.400 None 0.960 25 1 1989 2019
Entrez Id: 5015
Gene Symbol: OTX2
OTX2 		P32243 orthodenticle homeobox 2 Transcription factor 200 0.514 0.808 0.92 0.400 None 1.000 25 0 1999 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.400 None 0.960 25 0 2000 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 15 0 2005 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 14 0 2008 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.100 None 1.000 13 0 2002 2019
Entrez Id: 51684
Gene Symbol: SUFU
SUFU 		Q9UMX1 SUFU negative regulator of hedgehog signaling 272 0.493 0.769 1.00 0.400 None 1.000 12 0 2004 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 1.000 12 0 2005 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 12 0 2005 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.400 None 1.000 12 0 2005 2018
Entrez Id: 648
Gene Symbol: BMI1
BMI1 		P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.100 None 1.000 11 0 2007 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 1.000 11 0 1996 2019
Entrez Id: 1021
Gene Symbol: CDK6
CDK6 		Q00534 cyclin dependent kinase 6 Kinase 266 0.471 0.731 0.98 0.380 None 1.000 10 0 2005 2018
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 10 0 2012 2020
Entrez Id: 6608
Gene Symbol: SMO
SMO 		Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.090 None 1.000 9 1 2000 2020
Entrez Id: 474
Gene Symbol: ATOH1
ATOH1 		Q92858 atonal bHLH transcription factor 1 Enzyme 53 0.633 0.500 1.8E-02 0.390 None 1.000 9 0 2008 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.380 None 1.000 9 0 1995 2020
Entrez Id: 5978
Gene Symbol: REST
REST 		Q13127 RE1 silencing transcription factor Transcription factor 178 0.535 0.808 0.99 0.090 None 0.889 9 0 2000 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.370 None 1.000 8 0 2001 2018
Entrez Id: 8842
Gene Symbol: PROM1
PROM1 		O43490 prominin 1 Transporter 477 0.410 0.846 1.9E-22 0.080 None 1.000 8 0 2009 2019