Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
Q9Y6Q9 nuclear receptor coactivator 3 Kinase 142 0.522 0.654 0.54 0.300 None 1.000 1 0 2013 2013
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.300 None 1.000 1 0 2006 2006
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.300 None 1.000 1 0 2006 2006
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 1.000 1 0 2006 2006
Entrez Id: 5352
Gene Symbol: PLOD2
PLOD2
O00469 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Enzyme 114 0.559 0.654 6.7E-08 0.300 None 1.000 1 0 2005 2005
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.300 None 1.000 1 0 2015 2015
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.300 None 1.000 1 0 2006 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.300 None 1.000 1 0 2006 2006
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 1.000 4 0 2017 2019
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.040 None 1.000 4 0 2017 2019
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 G-protein coupled receptor 197 0.509 0.846 6.5E-06 0.030 None 1.000 3 0 2017 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.030 None 1.000 3 0 2019 2019
Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1
Q01844 EWS RNA binding protein 1 Nucleic acid binding 251 0.474 0.692 1.00 0.030 None 1.000 3 0 2012 2015
Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
Q99572 purinergic receptor P2X 7 Ion channel 337 0.450 0.808 3.3E-11 0.030 None 1.000 3 0 2015 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.020 None 1.000 2 0 2003 2007
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
O15455 toll like receptor 3 Receptor 393 0.427 0.885 1.6E-07 0.020 None 1.000 2 0 2020 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.020 None 1.000 2 0 2014 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.020 None 1.000 2 0 2017 2018
Entrez Id: 5179
Gene Symbol: PENK
PENK
P01210 proenkephalin Signaling 124 0.560 0.808 2.1E-04 0.020 None 1.000 2 0 2002 2017
Entrez Id: 27086
Gene Symbol: FOXP1
FOXP1
Q9H334 forkhead box P1 317 0.460 0.808 1.00 0.020 None 1.000 2 0 1999 2000
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.020 None 1.000 2 0 2019 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.020 None 1.000 2 0 2019 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.020 None 1.000 2 0 2019 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2018 2019
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.020 None 1.000 2 0 2016 2019