Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.700 None 1.000 72 6 1994 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.600 None 0.980 147 11 1991 2020
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase Enzyme 356 0.453 0.808 1.2E-15 0.530 None 1.000 4 1 2002 2015
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
O15550 lysine demethylase 6A Epigenetic regulator 238 0.498 0.769 1.00 0.520 None 1.000 3 0 2014 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.500 None 0.976 41 1 1999 2019
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1
Q9P212 phospholipase C epsilon 1 Enzyme 114 0.572 0.654 5.7E-11 0.500 None 0.941 34 10 2010 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.400 None 0.923 52 2 1994 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.400 None 1.000 51 2 1995 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 39 1 2000 2018
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.400 None 0.970 33 3 1996 2019
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 224 0.502 0.846 9.9E-07 0.400 None 1.000 23 4 1997 2019
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.400 None 1.000 19 0 2009 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.400 None 1.000 14 0 2005 2019
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.400 None 1.000 13 4 1998 2019
Entrez Id: 113278
Gene Symbol: SLC52A3
SLC52A3
Q9NQ40 solute carrier family 52 member 3 Transporter 103 0.610 0.654 1.9E-02 0.400 None 0.923 13 4 2010 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.400 None 0.846 13 0 2014 2020
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.400 None 0.750 12 3 2002 2017
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.400 None 1.000 11 2 2003 2014
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.400 None 1.000 11 0 2009 2020
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 336 0.435 0.846 0.400 None 0.900 10 2 2015 2019
Entrez Id: 340061
Gene Symbol: STING1
STING1
Q86WV6 stimulator of interferon response cGAMP interactor 1 159 0.522 0.769 1.2E-03 0.400 None 1.000 1 1 2014 2014
Entrez Id: 482
Gene Symbol: ATP1B2
ATP1B2
P14415 ATPase Na+/K+ transporting subunit beta 2 Transporter 28 0.705 0.308 7.4E-02 0.400 None 1.000 1 1 2014 2014
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.390 None 0.800 10 0 2011 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.390 None 0.889 9 0 2004 2018
Entrez Id: 4017
Gene Symbol: LOXL2
LOXL2
Q9Y4K0 lysyl oxidase like 2 149 0.527 0.731 3.4E-07 0.370 None 1.000 7 0 2012 2019