Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
Q8NFG4 folliculin 160 0.537 0.885 0.79 0.900 None 0.938 16 8 2002 2020
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.800 None 0.972 289 14 1989 2019
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 292 0.478 0.846 0.96 0.720 strong 1.000 2 5 1994 1999
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 Epigenetic regulator 105 0.566 0.615 1.00 0.700 None 1.000 56 1 2011 2020
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.700 None 0.957 47 0 2003 2019
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.640 None 1.000 4 2 2003 2011
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.600 None 0.984 64 0 2005 2020
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.600 None 0.982 56 0 2011 2019
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.600 None 0.969 32 2 1999 2020
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.600 None 1.000 14 0 1995 2020
Entrez Id: 8242
Gene Symbol: KDM5C
KDM5C
P41229 lysine demethylase 5C 119 0.581 0.538 1.00 0.600 None 1.000 11 0 2011 2017
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
P35680 HNF1 homeobox B Nucleic acid binding 279 0.473 0.808 1.00 0.550 None 0.833 6 0 1999 2017
Entrez Id: 7030
Gene Symbol: TFE3
TFE3
P19532 transcription factor binding to IGHM enhancer 3 118 0.542 0.654 0.98 0.400 None 0.988 82 0 2001 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.951 81 5 1991 2019
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
Q99814 endothelial PAS domain protein 1 Transcription factor 293 0.454 0.731 0.60 0.400 None 0.930 57 5 2001 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.400 None 1.000 49 0 2006 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.400 None 1.000 37 0 1998 2020
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor Kinase 623 0.378 0.885 1.00 0.400 None 0.972 36 0 2001 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.964 28 0 1993 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.400 None 0.929 14 0 2012 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.400 None 0.929 14 0 2000 2018
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.400 None 1.000 13 0 1999 2018
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.400 None 1.000 13 0 2001 2020
Entrez Id: 4286
Gene Symbol: MITF
MITF
O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.400 None 1.000 12 2 2009 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 11 0 2002 2019