Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
Q8NFG4 folliculin 154 0.567 0.655 0.92 0.730 1.000 5 1 2003 2014
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor 293 0.464 0.586 5.5E-02 0.700 0.946 121 4 1995 2018
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 73 0.590 0.517 1.00 0.700 1.000 28 1 2012 2018
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2 297 0.465 0.724 1.00 0.700 0.929 20 0 2004 2016
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 218 0.476 0.759 2.1E-12 0.610 1.000 2 1 2000 2009
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 hydrolase; protease 186 0.488 0.586 0.99 0.600 1.000 23 0 2012 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.600 1.000 11 0 2009 2018
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A nucleic acid binding; transcription factor 187 0.515 0.621 0.96 0.600 0 1
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 457 0.403 0.759 1.00 0.580 1.000 9 0 1995 2017
Entrez Id: 8242
Gene Symbol: KDM5C
KDM5C
P41229 lysine demethylase 5C transcription factor 103 0.619 0.483 1.00 0.580 1.000 9 0 2012 2016
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.570 1.000 8 2 2003 2018
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
Q99814 endothelial PAS domain protein 1 nucleic acid binding; transcription factor 153 0.509 0.586 0.50 0.400 0.846 14 0 2011 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.380 1.000 12 0 1999 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.380 1.000 9 0 2002 2016
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor 343 0.423 0.724 1.00 0.370 1.000 7 0 2010 2017
Entrez Id: 7030
Gene Symbol: TFE3
TFE3
P19532 transcription factor binding to IGHM enhancer 3 56 0.616 0.448 0.98 0.360 1.000 6 0 2002 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.340 1.000 4 0 2009 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.330 1.000 4 0 1995 2017
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.320 1.000 4 0 2008 2018
Entrez Id: 6921
Gene Symbol: ELOC
ELOC
Q15369 elongin C enzyme modulator 22 0.707 0.241 0.320 1.000 3 0 2013 2016
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 enzyme modulator 191 0.479 0.655 5.7E-02 0.320 1.000 3 0 2007 2011
Entrez Id: 317
Gene Symbol: APAF1
APAF1
O14727 apoptotic peptidase activating factor 1 106 0.545 0.655 7.4E-06 0.320 1.000 2 0 2007 2016
Entrez Id: 11236
Gene Symbol: RNF139
RNF139
Q8WU17 ring finger protein 139 20 0.707 0.207 0.51 0.320 1.000 2 0 2005 2007
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 enzyme modulator 290 0.463 0.690 1.00 0.320 0.500 2 0 2001 2017
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
Q92733 papillary renal cell carcinoma (translocation-associated) 11 0.762 0.103 0.96 0.320 1.000 2 0 2002 2003