Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.200 None 1.000 28 2 1991 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 1.000 22 72 1993 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.200 None 1.000 17 6 1994 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.200 None 1.000 15 0 1996 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.200 None 1.000 12 0 1996 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.200 None 1.000 12 4 2000 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.150 None 1.000 6 1 1995 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.130 None 1.000 4 10 2007 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.120 None 1.000 3 6 1994 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.120 None 1.000 3 4 2014 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.120 None 1.000 2 0 2012 2018
Entrez Id: 54894
Gene Symbol: RNF43
RNF43 		Q68DV7 ring finger protein 43 88 0.584 0.577 0.73 0.110 None 1.000 1 0 2013 2013
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.110 None 1.000 1 0 1998 1998
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM 		P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.110 None 1.000 1 0 2011 2011
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.110 None 1.000 1 0 2001 2001
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.923 13 0 2001 2017
Entrez Id: 5426
Gene Symbol: POLE
POLE 		Q07864 DNA polymerase epsilon, catalytic subunit 151 0.526 0.731 8.0E-27 0.100 None 1.000 1 2 2016 2016
Entrez Id: 10992
Gene Symbol: SF3B2
SF3B2 		Q13435 splicing factor 3b subunit 2 15 0.780 0.308 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 9968
Gene Symbol: MED12
MED12 		Q93074 mediator complex subunit 12 Transcription factor 340 0.476 0.769 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2 		P36507 mitogen-activated protein kinase kinase 2 Kinase 177 0.534 0.731 0.97 0.100 None 1.000 1 2 2016 2016
Entrez Id: 7307
Gene Symbol: U2AF1
U2AF1 		P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 67 0.604 0.577 0.99 0.100 None 1.000 1 1 2016 2016
Entrez Id: 10408
Gene Symbol: MYCNOS
MYCNOS 		P40205 MYCN opposite strand 28 0.700 0.462 0.100 None 1.000 1 1 2016 2016
Entrez Id: 4613
Gene Symbol: MYCN
MYCN 		P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 314 0.454 0.808 0.89 0.100 None 1.000 1 1 2016 2016
Entrez Id: 6256
Gene Symbol: RXRA
RXRA 		P19793 retinoid X receptor alpha Nuclear receptor 132 0.543 0.769 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 2778
Gene Symbol: GNAS
GNAS 		O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 536 0.420 0.885 0.68 0.100 None 1.000 1 2 2016 2016