Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.200 1.000 19 1 1994 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.200 0.941 18 5 1995 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.200 1.000 16 71 1993 2017
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.200 0.917 13 4 1997 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.200 1.000 10 0 1997 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.160 1.000 6 0 1997 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.150 1.000 6 1 1995 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.110 1.000 2 3 2016 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.110 1.000 2 10 2011 2016
Entrez Id: 7307
Gene Symbol: U2AF1
U2AF1
P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 nucleic acid binding 51 0.624 0.552 0.99 0.100 1 1 2016 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.100 1 6 2016 2016
Entrez Id: 6256
Gene Symbol: RXRA
RXRA
P19793 retinoid X receptor alpha nucleic acid binding; receptor; transcription factor 79 0.584 0.621 1.00 0.100 1 1 2016 2016
Entrez Id: 10992
Gene Symbol: SF3B2
SF3B2
Q13435 splicing factor 3b subunit 2 9 0.799 0.276 1.00 0.100 1 1 2016 2016
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
P36507 mitogen-activated protein kinase kinase 2 177 0.559 0.586 0.97 0.100 1 2 2016 2016
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 394 0.443 0.793 0.71 0.100 1 2 2016 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 66 0.616 0.345 1.8E-25 0.100 1 2 2016 2016
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
P04198 MYCN proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 232 0.481 0.759 0.89 0.100 1 1 2016 2016
Entrez Id: 9968
Gene Symbol: MED12
MED12
Q93074 mediator complex subunit 12 nucleic acid binding; transcription factor 266 0.528 0.655 1.00 0.100 1 1 2016 2016
Entrez Id: 23022
Gene Symbol: PALLD
PALLD
Q8WX93 palladin, cytoskeletal associated protein transmembrane receptor regulatory/adaptor protein 48 0.652 0.379 6.4E-06 0.100 0 0
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 122 0.569 0.552 7.3E-20 0.100 0 0
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.080 1.000 8 0 2001 2017
Entrez Id: 4585
Gene Symbol: MUC4
MUC4
Q99102 mucin 4, cell surface associated 117 0.533 0.621 1.3E-44 0.070 1.000 7 0 2002 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.070 1.000 7 0 2004 2011
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 cystic fibrosis transmembrane conductance regulator transporter 307 0.453 0.793 1.1E-57 0.060 0.833 6 0 1990 2015
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1
P17096 high mobility group AT-hook 1 nucleic acid binding 124 0.532 0.552 0.83 0.060 1.000 6 0 2007 2015