Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7084
Gene Symbol: TK2
TK2
O00142 thymidine kinase 2 Kinase 143 0.585 0.615 3.9E-07 0.200 None 1.000 19 2 2001 2015
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.140 None 1.000 13 2 2008 2017
Entrez Id: 26235
Gene Symbol: FBXL4
FBXL4
Q9UKA2 F-box and leucine rich repeat protein 4 55 0.695 0.423 1.1E-08 0.120 None 1.000 5 1 2013 2019
Entrez Id: 7019
Gene Symbol: TFAM
TFAM
Q00059 transcription factor A, mitochondrial 147 0.529 0.731 0.17 0.120 None 1.000 2 1 1994 2011
Entrez Id: 1716
Gene Symbol: DGUOK
DGUOK
Q16854 deoxyguanosine kinase Kinase 112 0.593 0.500 3.7E-07 0.100 None 1.000 16 0 2002 2017
Entrez Id: 4358
Gene Symbol: MPV17
MPV17
P39210 mitochondrial inner membrane protein MPV17 Receptor 134 0.595 0.577 9.7E-11 0.100 None 1.000 13 0 2006 2017
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2
Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 136 0.566 0.654 2.3E-03 0.050 None 1.000 5 0 2007 2017
Entrez Id: 56652
Gene Symbol: TWNK
TWNK
Q96RR1 twinkle mtDNA helicase Enzyme 245 0.516 0.692 3.2E-03 0.040 None 1.000 4 0 2007 2019
Entrez Id: 50484
Gene Symbol: RRM2B
RRM2B
Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 238 0.527 0.769 2.4E-03 0.040 None 1.000 4 0 2007 2020
Entrez Id: 11232
Gene Symbol: POLG2
POLG2
Q9UHN1 DNA polymerase gamma 2, accessory subunit Enzyme 158 0.558 0.769 1.5E-10 0.030 None 1.000 3 1 2016 2019
Entrez Id: 8802
Gene Symbol: SUCLG1
SUCLG1
P53597 succinate-CoA ligase GDP/ADP-forming subunit alpha 47 0.666 0.423 4.8E-04 0.030 None 1.000 3 0 2008 2011
Entrez Id: 8526
Gene Symbol: DGKE
DGKE
P52429 diacylglycerol kinase epsilon Enzyme 41 0.674 0.538 5.5E-06 0.020 None 1.000 2 0 2002 2005
Entrez Id: 89874
Gene Symbol: SLC25A21
SLC25A21
Q9BQT8 solute carrier family 25 member 21 Transporter 54 0.636 0.654 1.4E-11 0.020 None 1.000 2 0 2018 2019
Entrez Id: 1607
Gene Symbol: DGKB
DGKB
Q9Y6T7 diacylglycerol kinase beta Enzyme 32 0.716 0.423 0.53 0.020 None 1.000 2 0 2002 2005
Entrez Id: 9804
Gene Symbol: TOMM20
TOMM20
Q15388 translocase of outer mitochondrial membrane 20 Transporter 21 0.743 0.462 2.7E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 57132
Gene Symbol: CHMP1B
CHMP1B
Q7LBR1 charged multivesicular body protein 1B Transporter 24 0.736 0.462 0.73 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6606
Gene Symbol: SMN1
SMN1
Q16637 survival of motor neuron 1, telomeric Epigenetic regulator 317 0.454 0.769 1.6E-02 0.010 None 1.000 1 0 2002 2002
Entrez Id: 6607
Gene Symbol: SMN2
SMN2
Q16637 survival of motor neuron 2, centromeric 299 0.459 0.769 0.10 0.010 None 1.000 1 0 2002 2002
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2011 2011
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2005 2005
Entrez Id: 55687
Gene Symbol: TRMU
TRMU
O75648 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 50 0.716 0.385 1.5E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 142
Gene Symbol: PARP1
PARP1
P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.010 None 1.000 1 0 2008 2008
Entrez Id: 1431
Gene Symbol: CS
CS
O75390 citrate synthase Enzyme 87 0.590 0.654 0.98 0.010 None 1.000 1 0 2012 2012
Entrez Id: 1841
Gene Symbol: DTYMK
DTYMK
P23919 deoxythymidylate kinase Kinase 28 0.705 0.231 6.2E-05 0.010 None 1.000 1 0 2019 2019