Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 1.000 definitive 0.969 92 69 1993 2017
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A
P36894 bone morphogenetic protein receptor type 1A kinase; receptor; transferase 87 0.580 0.517 0.85 1.000 definitive 1.000 38 20 2000 2017
Entrez Id: 2022
Gene Symbol: ENG
ENG
P17813 endoglin 249 0.477 0.655 1.00 0.550 limited 0.800 7 0 2005 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 0.933 15 0 1997 2016
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 kinase; receptor; transferase 130 0.570 0.621 8.2E-04 0.030 1.000 3 0 2007 2014
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.030 1.000 3 0 2000 2013
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 nucleic acid binding; transcription factor 170 0.499 0.586 0.53 0.020 0.500 2 0 2001 2009
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.020 1.000 2 0 1993 1997
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.010 < 0.001 1 0 2013 2013
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta kinase; transferase 487 0.386 0.862 1.00 0.010 1.000 1 0 2017 2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma kinase; transferase 490 0.385 0.862 1.5E-06 0.010 1.000 1 0 2017 2017
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 386 0.435 0.759 1.00 0.010 1.000 1 0 2000 2000
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.010 1.000 1 0 2009 2009
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor enzyme modulator 137 0.521 0.724 8.7E-04 0.010 1.000 1 0 2014 2014
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
O60565 gremlin 1, DAN family BMP antagonist 77 0.602 0.517 0.50 0.010 1.000 1 0 2012 2012
Entrez Id: 7905
Gene Symbol: REEP5
REEP5
Q00765 receptor accessory protein 5 receptor; transporter 40 0.645 0.517 7.5E-04 0.010 1.000 1 0 1993 1993
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
P01135 transforming growth factor alpha signaling molecule 290 0.447 0.724 0.74 0.010 1.000 1 0 2013 2013
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta kinase; transferase 468 0.389 0.862 1.00 0.010 1.000 1 0 2017 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.010 1.000 1 0 2017 2017
Entrez Id: 650
Gene Symbol: BMP2
BMP2
P12643 bone morphogenetic protein 2 signaling molecule 214 0.491 0.759 0.99 0.010 1.000 1 0 2008 2008
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
Q13873 bone morphogenetic protein receptor type 2 kinase; receptor; transferase 96 0.573 0.552 1.00 0.010 1.000 1 0 2004 2004
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 156 0.504 0.655 0.99 0.010 1.000 1 0 1999 1999
Entrez Id: 1994
Gene Symbol: ELAVL1
ELAVL1
Q15717 ELAV like RNA binding protein 1 56 0.607 0.621 0.99 0.010 1.000 1 0 2009 2009
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 135 0.557 0.483 2.0E-02 0.010 1.000 1 0 2013 2013
Entrez Id: 4090
Gene Symbol: SMAD5
SMAD5
Q99717 SMAD family member 5 transcription factor 29 0.681 0.483 1.00 0.010 1.000 1 0 1999 1999