Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.700 definitive 0.944 36 2 2006 2019
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.350 definitive 0.938 16 4 2001 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.310 definitive 1.000 13 0 1991 2018
Entrez Id: 5888
Gene Symbol: RAD51
RAD51
Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.100 None 0.909 11 1 1999 2016
Entrez Id: 84464
Gene Symbol: SLX4
SLX4
Q8IY92 SLX4 structure-specific endonuclease subunit 123 0.565 0.731 1.6E-22 0.330 limited 1.000 10 0 2011 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.320 disputed 1.000 9 1 2010 2019
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D
O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.510 limited 1.000 9 1 2000 2019
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Q92878 RAD50 double strand break repair protein 110 0.556 0.808 3.4E-27 0.340 limited 0.714 7 0 2003 2017
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.320 disputed 1.000 7 1 1998 2017
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2
O43543 X-ray repair cross complementing 2 187 0.512 0.731 4.0E-07 0.530 limited 1.000 7 1 1999 2019
Entrez Id: 348654
Gene Symbol: GEN1
GEN1
Q17RS7 GEN1 Holliday junction 5' flap endonuclease 35 0.682 0.500 3.7E-15 0.300 disputed 1.000 6 0 2011 2016
Entrez Id: 60500
Gene Symbol: BRCA3
BRCA3
breast cancer 3 27 0.705 0.269 0.060 None 1.000 6 0 2007 2017
Entrez Id: 142
Gene Symbol: PARP1
PARP1
P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.050 None 1.000 5 0 2012 2015
Entrez Id: 60561
Gene Symbol: RINT1
RINT1
Q6NUQ1 RAD50 interactor 1 19 0.743 0.231 5.3E-13 0.300 disputed 1.000 5 0 2001 2016
Entrez Id: 115761
Gene Symbol: ARL11
ARL11
Q969Q4 ADP ribosylation factor like GTPase 11 35 0.670 0.423 5.3E-03 0.040 None 1.000 4 4 2006 2011
Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2
P13942 collagen type XI alpha 2 chain 399 0.435 0.846 0.70 0.040 None 1.000 4 0 2012 2015
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.040 None 0.750 4 2 2006 2016
Entrez Id: 1647
Gene Symbol: GADD45A
GADD45A
P24522 growth arrest and DNA damage inducible alpha 151 0.526 0.769 4.4E-02 0.030 None 0.667 3 0 2004 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.030 None 1.000 3 0 2005 2008
Entrez Id: 5245
Gene Symbol: PHB
PHB
P35232 prohibitin 177 0.511 0.846 0.76 0.030 None 1.000 3 0 1992 2008
Entrez Id: 55655
Gene Symbol: NLRP2
NLRP2
Q9NX02 NLR family pyrin domain containing 2 155 0.515 0.731 1.4E-38 0.030 None 0.667 3 0 2012 2014
Entrez Id: 11214
Gene Symbol: AKAP13
AKAP13
Q12802 A-kinase anchoring protein 13 73 0.626 0.615 0.93 0.020 None 1.000 2 3 2006 2007
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.020 None 0.500 2 0 2003 2010
Entrez Id: 2177
Gene Symbol: FANCD2
FANCD2
Q9BXW9 FA complementation group D2 272 0.479 0.885 1.1E-30 0.020 None 1.000 2 0 2008 2017
Entrez Id: 220972
Gene Symbol: MARCHF8
MARCHF8
Q5T0T0 membrane associated ring-CH-type finger 8 87 0.590 0.692 5.9E-07 0.020 None 1.000 2 0 2014 2016