Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.300 0 0
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.100 None 0 1
Entrez Id: 8438
Gene Symbol: RAD54L
RAD54L
Q92698 RAD54 like 46 0.633 0.423 2.4E-15 0.300 None 0 0
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.300 0 0
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
Q96BI1 solute carrier family 22 member 18 Transporter 76 0.595 0.692 6.5E-06 0.300 None 0 0
Entrez Id: 5617
Gene Symbol: PRL
PRL
P01236 prolactin Signaling 506 0.406 0.885 2.9E-07 0.020 None 1.000 2 0 1989 2006
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.010 None 1.000 1 0 1989 1989
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.310 definitive 1.000 13 0 1991 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.969 32 6 1992 2019
Entrez Id: 5245
Gene Symbol: PHB
PHB
P35232 prohibitin 177 0.511 0.846 0.76 0.030 None 1.000 3 0 1992 2008
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.400 None 0.946 297 12 1993 2019
Entrez Id: 3294
Gene Symbol: HSD17B2
HSD17B2
P37059 hydroxysteroid 17-beta dehydrogenase 2 Enzyme 42 0.656 0.385 1.8E-10 0.030 None 1.000 3 0 1994 2007
Entrez Id: 3292
Gene Symbol: HSD17B1
HSD17B1
P14061 hydroxysteroid 17-beta dehydrogenase 1 Enzyme 69 0.610 0.615 1.3E-04 0.020 None 1.000 2 0 1994 1994
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.400 None 0.961 205 3 1995 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.070 None 0.857 7 1 1995 2013
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.300 disputed 1.000 4 0 1995 2018
Entrez Id: 5793
Gene Symbol: PTPRG
PTPRG
P23470 protein tyrosine phosphatase receptor type G Enzyme 70 0.619 0.731 5.1E-06 0.010 None 1.000 1 0 1996 1996
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad diadenosine triphosphatase 337 0.444 0.846 5.7E-03 0.010 None 1.000 1 0 1996 1996
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.400 definitive 1.000 22 2 1998 2019
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.320 disputed 1.000 7 1 1998 2017
Entrez Id: 7251
Gene Symbol: TSG101
TSG101
Q99816 tumor susceptibility 101 Enzyme 80 0.588 0.615 0.34 0.030 None 1.000 3 0 1998 2002
Entrez Id: 5888
Gene Symbol: RAD51
RAD51
Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.100 None 0.909 11 1 1999 2016
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2
O43543 X-ray repair cross complementing 2 187 0.512 0.731 4.0E-07 0.530 limited 1.000 7 1 1999 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.400 definitive 0.939 33 0 2000 2019
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D
O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.510 limited 1.000 9 1 2000 2019