Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.900 0.953 129 8 1992 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.700 0.951 129 3 1992 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.700 0.965 85 0 1996 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.700 0.929 58 2 1996 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.680 1.000 9 0 1999 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.600 1.000 76 6 1995 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.600 1.000 22 0 2002 2018
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1
P00995 serine peptidase inhibitor, Kazal type 1 125 0.536 0.621 0.33 0.500 0.818 11 1 2003 2017
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 nucleic acid binding; transcription factor; transferase 322 0.489 0.828 1.00 0.500 0 0
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 0.976 86 0 1986 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 1.000 52 0 2003 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.400 0.978 46 2 2001 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.955 46 0 1999 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.897 30 0 1995 2017
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.400 1.000 27 0 2001 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 signaling molecule 847 0.336 0.931 0.17 0.400 0.952 22 0 1996 2018
Entrez Id: 28
Gene Symbol: ABO
ABO
P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase transferase 193 0.491 0.828 0.400 1.000 19 0 2009 2018
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Q13421 mesothelin extracellular matrix protein 86 0.565 0.483 8.2E-23 0.400 0.944 18 0 2002 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.400 0.938 17 0 1995 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 122 0.569 0.552 7.3E-20 0.400 0.938 17 0 2009 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 467 0.389 0.862 2.1E-07 0.400 1.000 16 0 1999 2017
Entrez Id: 6750
Gene Symbol: SST
SST
P61278 somatostatin signaling molecule 265 0.457 0.724 0.36 0.400 1.000 16 0 1986 2011
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 135 0.557 0.483 2.0E-02 0.400 1.000 14 0 2004 2015
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.400 1.000 14 1 2005 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 0.909 12 0 2002 2014