Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
P01042 kininogen 1 enzyme modulator 159 0.530 0.862 3.6E-10 0.300 17 0 1989 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.300 11 0 1995 2016
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 252 0.473 0.793 0.75 0.300 9 0 1997 2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.300 6 0 1995 2016
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 transporter 173 0.532 0.724 8.2E-17 0.300 4 0 2002 2013
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 475 0.398 0.897 3.4E-02 0.300 4 0 1997 2011
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha signaling molecule 274 0.456 0.828 1.4E-02 0.300 4 0 2003 2016
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
P46663 bradykinin receptor B1 receptor 61 0.642 0.517 4.4E-03 0.300 3 0 2008 2010
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
P30411 bradykinin receptor B2 receptor 79 0.619 0.621 0.13 0.300 3 0 2008 2010
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1
P54289 calcium voltage-gated channel auxiliary subunit alpha2delta 1 48 0.696 0.379 1.00 0.300 3 0 2001 2013
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
Q02156 protein kinase C epsilon calcium-binding protein; kinase; transfer/carrier protein; transferase 88 0.604 0.552 1.00 0.300 3 0 2002 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.300 3 0 1995 2008
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
O75762 transient receptor potential cation channel subfamily A member 1 74 0.639 0.621 9.2E-33 0.300 3 0 2008 2013
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 kinase; transferase 345 0.429 0.828 1.0E-01 0.300 2 0 2003 2016
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 531 0.385 0.931 1.5E-14 0.300 2 0 2008 2009
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
P28223 5-hydroxytryptamine receptor 2A receptor 211 0.488 0.759 0.48 0.300 2 0 2008 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.300 2 0 2007 2008
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 kinase; transferase 525 0.387 0.862 1.00 0.300 2 0 2003 2016
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.300 2 0 1995 1999
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
Q13519 prepronociceptin signaling molecule 52 0.672 0.414 1.0E-02 0.300 2 0 2003 2009
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 961 0.320 0.931 6.5E-03 0.300 2 0 1995 2007
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
P25103 tachykinin receptor 1 105 0.559 0.724 3.3E-04 0.300 2 0 2005 2007
Entrez Id: 5582
Gene Symbol: PRKCG
PRKCG
P05129 protein kinase C gamma calcium-binding protein; kinase; transfer/carrier protein; transferase 63 0.642 0.345 1.00 0.300 2 0 2010 2016
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 receptor 110 0.554 0.621 7.0E-06 0.300 2 0 2008 2008
Entrez Id: 7056
Gene Symbol: THBD
THBD
P07204 thrombomodulin 165 0.505 0.759 0.23 0.300 1 0 2016 2016