Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.800 strong 0.969 134 2 1995 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 189 0.495 0.586 2.2E-05 0.800 strong 0.957 49 7 1999 2017
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 665 0.398 0.759 1.00 0.700 1.000 28 4 1995 2018
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component nucleic acid binding 154 0.526 0.586 1.2E-27 0.700 strong 1.000 12 0 1999 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.600 0.954 87 4 1991 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 nucleic acid binding 356 0.424 0.759 5.1E-05 0.600 strong 0.939 82 2 1993 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 nucleic acid binding 320 0.437 0.690 0.91 0.600 strong 0.927 55 4 1993 2017
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 enzyme modulator 140 0.511 0.759 1.00 0.540 1.000 5 0 2002 2013
Entrez Id: 8405
Gene Symbol: SPOP
SPOP
O43791 speckle type BTB/POZ protein 37 0.656 0.207 1.00 0.520 1.000 3 0 2013 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.500 0.909 12 0 1994 2016
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 nucleic acid binding 158 0.507 0.621 8.1E-31 0.450 0.800 5 1 1996 2002
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor nucleic acid binding; receptor; transcription factor 230 0.467 0.690 7.2E-02 0.400 0.976 42 2 1992 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.962 27 0 1993 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 0.933 15 0 1991 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 66 0.616 0.345 1.8E-25 0.400 1.000 13 1 2013 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.400 0.818 11 0 1998 2018
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 211 0.505 0.724 1.00 0.380 1.000 9 0 2011 2016
Entrez Id: 5424
Gene Symbol: POLD1
POLD1
P28340 DNA polymerase delta 1, catalytic subunit 144 0.546 0.655 2.2E-06 0.380 1.000 8 1 2013 2016
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
P37275 zinc finger E-box binding homeobox 1 transcription factor 167 0.501 0.621 0.97 0.360 1.000 6 0 2006 2016
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 nucleic acid binding; receptor; transcription factor 297 0.445 0.828 5.4E-08 0.350 1.000 6 4 2001 2015
Entrez Id: 6770
Gene Symbol: STAR
STAR
P49675 steroidogenic acute regulatory protein 76 0.584 0.483 8.8E-11 0.340 0.750 4 0 2004 2017
Entrez Id: 406985
Gene Symbol: MIR200C
MIR200C
microRNA 200c 114 0.536 0.621 0.330 1.000 4 0 2012 2018
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor 373 0.433 0.828 0.99 0.330 1.000 4 0 1999 2016
Entrez Id: 57016
Gene Symbol: AKR1B10
AKR1B10
O60218 aldo-keto reductase family 1 member B10 oxidoreductase 76 0.588 0.655 8.1E-09 0.330 1.000 3 0 2009 2017
Entrez Id: 1583
Gene Symbol: CYP11A1
CYP11A1
P05108 cytochrome P450 family 11 subfamily A member 1 141 0.555 0.552 4.1E-07 0.330 1.000 3 0 2010 2013