Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 265 0.492 0.724 7.3E-03 0.500 0.986 93 12 1998 2018
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.500 0.970 75 8 1993 2018
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
P26358 DNA methyltransferase 1 299 0.438 0.759 1.00 0.450 1.000 5 0 2011 2016
Entrez Id: 1356
Gene Symbol: CP
CP
P00450 ceruloplasmin oxidoreductase 190 0.500 0.586 2.8E-09 0.410 1.000 2 0 2003 2016
Entrez Id: 2896
Gene Symbol: GRN
GRN
P28799 granulin precursor 251 0.476 0.724 5.3E-02 0.400 0.966 43 2 2006 2016
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
Q9NZC2 triggering receptor expressed on myeloid cells 2 178 0.572 0.552 4.0E-09 0.380 1.000 8 4 2008 2016
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 transporter 237 0.484 0.690 1.00 0.330 1.000 4 0 1992 2016
Entrez Id: 23315
Gene Symbol: SLC9A8
SLC9A8
Q9Y2E8 solute carrier family 9 member A8 11 0.762 0.241 1.9E-10 0.300 1 0 2009 2009
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.200 0.891 484 2 1994 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 calcium-binding protein; hydrolase; protease; signaling molecule 268 0.490 0.690 0.98 0.200 0.898 56 17 1990 2018
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 310 0.474 0.897 7.2E-04 0.200 0.900 43 3 1991 2015
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha chaperone; membrane traffic protein 176 0.513 0.793 0.90 0.200 1.000 29 2 2001 2017
Entrez Id: 9445
Gene Symbol: ITM2B
ITM2B
Q9Y287 integral membrane protein 2B 58 0.667 0.448 0.65 0.200 0.960 26 0 1999 2016
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch 3 312 0.469 0.690 0.87 0.200 1.000 17 1 1996 2016
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2
P49810 presenilin 2 hydrolase; protease; signaling molecule 108 0.567 0.517 2.4E-03 0.200 0.857 14 3 1997 2017
Entrez Id: 6683
Gene Symbol: SPAST
SPAST
Q9UBP0 spastin cytoskeletal protein 93 0.604 0.517 1.00 0.160 0.833 6 0 1998 2011
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
Q9NQ11 ATPase cation transporting 13A2 83 0.611 0.276 6.7E-09 0.160 1.000 6 0 2006 2016
Entrez Id: 2332
Gene Symbol: FMR1
FMR1
Q06787 fragile X mental retardation 1 nucleic acid binding 288 0.492 0.690 0.69 0.160 1.000 6 0 2007 2015
Entrez Id: 7276
Gene Symbol: TTR
TTR
P02766 transthyretin transfer/carrier protein; transporter 258 0.471 0.897 0.55 0.140 1.000 4 0 2001 2016
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 265 0.521 0.724 5.6E-06 0.140 1.000 4 0 2013 2016
Entrez Id: 5274
Gene Symbol: SERPINI1
SERPINI1
Q99574 serpin family I member 1 enzyme modulator 49 0.642 0.310 3.0E-02 0.130 1.000 3 0 2004 2017
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 167 0.500 0.724 3.9E-03 0.130 1.000 3 0 1996 2010
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced putative kinase 1 kinase; receptor; transferase 96 0.577 0.586 1.0E-10 0.130 1.000 3 0 2005 2010
Entrez Id: 6620
Gene Symbol: SNCB
SNCB
Q16143 synuclein beta chaperone; membrane traffic protein 22 0.707 0.241 5.9E-02 0.130 1.000 3 0 2011 2012
Entrez Id: 10715
Gene Symbol: CERS1
CERS1
P27544 ceramide synthase 1 28 0.685 0.310 9.8E-02 0.120 1.000 2 0 2015 2016