|
| Entrez Id: |
351 |
| Gene Symbol: |
APP |
APP
|
P05067
|
amyloid beta precursor protein
|
Enzyme modulator
|
485
|
0.422 |
0.846 |
4.7E-02 |
0.700 |
strong
|
0.964 |
83
|
10
|
1993 |
2020 |
|
| Entrez Id: |
54209 |
| Gene Symbol: |
TREM2 |
TREM2
|
Q9NZC2
|
triggering receptor expressed on myeloid cells 2
|
|
239
|
0.519 |
0.769 |
3.3E-09 |
0.700 |
strong
|
1.000 |
19
|
5
|
2005 |
2020 |
|
| Entrez Id: |
4137 |
| Gene Symbol: |
MAPT |
MAPT
|
P10636
|
microtubule associated protein tau
|
|
469
|
0.446 |
0.923 |
6.0E-03 |
0.500 |
None
|
0.992 |
127
|
13
|
1995 |
2020 |
|
| Entrez Id: |
5621 |
| Gene Symbol: |
PRNP |
PRNP
|
F7VJQ1 P04156
|
prion protein
|
|
426
|
0.445 |
0.923 |
6.3E-04 |
0.500 |
strong
|
0.958 |
48
|
4
|
1991 |
2019 |
|
| Entrez Id: |
2896 |
| Gene Symbol: |
GRN |
GRN
|
P28799
|
granulin precursor
|
|
412
|
0.435 |
0.846 |
7.0E-02 |
0.500 |
None
|
1.000 |
46
|
4
|
2006 |
2019 |
|
| Entrez Id: |
4854 |
| Gene Symbol: |
NOTCH3 |
NOTCH3
|
Q9UM47
|
notch receptor 3
|
|
418
|
0.435 |
0.808 |
0.41 |
0.500 |
strong
|
1.000 |
20
|
1
|
1996 |
2017 |
|
| Entrez Id: |
5664 |
| Gene Symbol: |
PSEN2 |
PSEN2
|
P49810
|
presenilin 2
|
Enzyme
|
146
|
0.550 |
0.654 |
5.4E-04 |
0.500 |
strong
|
1.000 |
17
|
3
|
1997 |
2018 |
|
| Entrez Id: |
1471 |
| Gene Symbol: |
CST3 |
CST3
|
P01034
|
cystatin C
|
|
370
|
0.436 |
0.808 |
3.9E-03 |
0.460 |
limited
|
1.000 |
6
|
0
|
1996 |
2019 |
|
| Entrez Id: |
1786 |
| Gene Symbol: |
DNMT1 |
DNMT1
|
P26358
|
DNA methyltransferase 1
|
Epigenetic regulator
|
496
|
0.406 |
0.885 |
1.00 |
0.450 |
None
|
1.000 |
5
|
0
|
2011 |
2015 |
|
| Entrez Id: |
1356 |
| Gene Symbol: |
CP |
CP
|
P00450
|
ceruloplasmin
|
Enzyme
|
283
|
0.466 |
0.846 |
4.2E-10 |
0.410 |
None
|
1.000 |
2
|
0
|
2003 |
2015 |
|
| Entrez Id: |
5654 |
| Gene Symbol: |
HTRA1 |
HTRA1
|
Q92743
|
HtrA serine peptidase 1
|
Enzyme
|
164
|
0.532 |
0.692 |
4.9E-04 |
0.400 |
strong
|
1.000 |
1
|
0
|
2014 |
2014 |
|
| Entrez Id: |
2521 |
| Gene Symbol: |
FUS |
FUS
|
P35637
|
FUS RNA binding protein
|
Nucleic acid binding
|
301
|
0.470 |
0.846 |
1.00 |
0.380 |
None
|
1.000 |
9
|
0
|
2009 |
2017 |
|
| Entrez Id: |
6531 |
| Gene Symbol: |
SLC6A3 |
SLC6A3
|
Q01959
|
solute carrier family 6 member 3
|
Transporter
|
373
|
0.453 |
0.885 |
1.00 |
0.360 |
None
|
1.000 |
7
|
1
|
1992 |
2019 |
|
| Entrez Id: |
7305 |
| Gene Symbol: |
TYROBP |
TYROBP
|
O43914
|
transmembrane immune signaling adaptor TYROBP
|
|
135
|
0.573 |
0.769 |
0.20 |
0.360 |
strong
|
1.000 |
7
|
0
|
2000 |
2018 |
|
| Entrez Id: |
1436 |
| Gene Symbol: |
CSF1R |
CSF1R
|
P07333
|
colony stimulating factor 1 receptor
|
Kinase
|
356
|
0.448 |
0.808 |
0.13 |
0.330 |
strong
|
1.000 |
4
|
0
|
2013 |
2019 |
|
| Entrez Id: |
1282 |
| Gene Symbol: |
COL4A1 |
COL4A1
|
P02462
|
collagen type IV alpha 1 chain
|
|
277
|
0.484 |
0.731 |
1.00 |
0.310 |
strong
|
1.000 |
2
|
0
|
2007 |
2016 |
|
| Entrez Id: |
23315 |
| Gene Symbol: |
SLC9A8 |
SLC9A8
|
Q9Y2E8
|
solute carrier family 9 member A8
|
Transporter
|
16
|
0.736 |
0.500 |
2.9E-10 |
0.300 |
None
|
1.000 |
1
|
0
|
2009 |
2009 |
|
| Entrez Id: |
348 |
| Gene Symbol: |
APOE |
APOE
|
P02649
|
apolipoprotein E
|
|
1049
|
0.338 |
0.962 |
1.9E-03 |
0.200 |
None
|
0.916 |
605
|
6
|
1994 |
2020 |
|
| Entrez Id: |
6622 |
| Gene Symbol: |
SNCA |
SNCA
|
P37840
|
synuclein alpha
|
Transporter
|
449
|
0.427 |
0.885 |
0.88 |
0.200 |
None
|
0.986 |
70
|
4
|
1998 |
2019 |
|
| Entrez Id: |
5663 |
| Gene Symbol: |
PSEN1 |
PSEN1
|
P49768
|
presenilin 1
|
Enzyme
|
369
|
0.469 |
0.846 |
0.97 |
0.200 |
None
|
0.983 |
58
|
22
|
1990 |
2019 |
|
| Entrez Id: |
203228 |
| Gene Symbol: |
C9orf72 |
C9orf72
|
Q96LT7
|
C9orf72-SMCR8 complex subunit
|
|
258
|
0.496 |
0.769 |
1.1E-06 |
0.200 |
None
|
0.941 |
34
|
0
|
2012 |
2020 |
|
| Entrez Id: |
9445 |
| Gene Symbol: |
ITM2B |
ITM2B
|
Q9Y287
|
integral membrane protein 2B
|
|
77
|
0.617 |
0.654 |
0.63 |
0.200 |
None
|
0.966 |
29
|
0
|
1999 |
2019 |
|
| Entrez Id: |
7415 |
| Gene Symbol: |
VCP |
VCP
|
P55072
|
valosin containing protein
|
|
376
|
0.469 |
0.923 |
1.00 |
0.200 |
None
|
0.958 |
24
|
3
|
2005 |
2019 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
Q5S007
|
leucine rich repeat kinase 2
|
Kinase
|
231
|
0.510 |
0.808 |
2.6E-30 |
0.200 |
None
|
0.812 |
16
|
2
|
2005 |
2019 |
|
| Entrez Id: |
25978 |
| Gene Symbol: |
CHMP2B |
CHMP2B
|
Q9UQN3
|
charged multivesicular body protein 2B
|
|
177
|
0.543 |
0.731 |
4.6E-06 |
0.190 |
None
|
1.000 |
9
|
0
|
2005 |
2016 |